ID A0A1V6Q525_9EURO Unreviewed; 586 AA.
AC A0A1V6Q525;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366042};
GN ORFNames=PENANT_c015G09240 {ECO:0000313|EMBL:OQD83886.1};
OS Penicillium antarcticum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=416450 {ECO:0000313|EMBL:OQD83886.1, ECO:0000313|Proteomes:UP000191672};
RN [1] {ECO:0000313|Proteomes:UP000191672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 31811 {ECO:0000313|Proteomes:UP000191672};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|RuleBase:RU366042}; Multi-pass membrane
CC protein {ECO:0000256|RuleBase:RU366042}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU366042}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD83886.1}.
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DR EMBL; MDYN01000015; OQD83886.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6Q525; -.
DR STRING; 416450.A0A1V6Q525; -.
DR OrthoDB; 73031at2759; -.
DR Proteomes; UP000191672; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF26; MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU366042};
KW Magnesium {ECO:0000256|RuleBase:RU366042};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366042};
KW Mitochondrion {ECO:0000256|RuleBase:RU366042};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366042};
KW Reference proteome {ECO:0000313|Proteomes:UP000191672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366042};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366042};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU366042}.
FT TRANSMEM 408..426
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
FT TRANSMEM 438..460
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
FT REGION 523..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 64629 MW; 79D535C9789B86C1 CRC64;
MLSPKLSAPS ASLLRFLHTQ SGFTTAPACA RPKRLGRDKP FSTVRASKLP SWTHPTTLCP
ARNDGAANGR SSAIRPMLVP SMPTQVTFSR LASTKSRPFL RRLFDLKRNK ASEYQNQRPA
GSGLVDEGTE GLFNIGRSLS AKASNELRIR CTEFDINGDV TLVNGEFRKL ELIAKYGLLP
RDLRKIDSST LPHILVRPSA ILINLLHLRV LIKADRVLVF DAYGSTDSYM QSLFIYDLEG
KLRQKQSQLA SQLSQSLPYE FRALEAVLIS VTSGLEEEFN GVRDPVVRVL RALEEDIDRD
KLRHLLIYSK KLGTFEQKAR LVRDAIDDLL EADDDLAAMY LSERSKGKER EEDDHQEVEM
LLESYHKVCD EIVQASGNLV TNIRNTEEVV KAILDANRNS LMLMDLKFSI GTLGLATGTL
FSALYGMNLK NFIEESDFGF GSVSVICFAL TGIVCVYGLA RLRKLQRVRM WGEAGVGGTS
PLAPLSPKRS AFGVNRNNWR ADSIEPVWGS LPGEGRPERM KRLREHAAAQ AASRNTKFGV
PNSPSATAAQ TPASAPHNKP RAEGSKGTEK ETAVHGEGNA KPGSHA
//
