ID   A0A1V6QCX2_9EURO        Unreviewed;       968 AA.
AC   A0A1V6QCX2;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN   ORFNames=PENSOL_c085G10355 {ECO:0000313|EMBL:OQD86847.1};
OS   Penicillium solitum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=60172 {ECO:0000313|EMBL:OQD86847.1, ECO:0000313|Proteomes:UP000191612};
RN   [1] {ECO:0000313|Proteomes:UP000191612}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 29525 {ECO:0000313|Proteomes:UP000191612};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQD86847.1}.
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DR   EMBL; MDYO01000085; OQD86847.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6QCX2; -.
DR   STRING; 60172.A0A1V6QCX2; -.
DR   OrthoDB; 2311449at2759; -.
DR   Proteomes; UP000191612; Unassembled WGS sequence.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR   PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Reference proteome {ECO:0000313|Proteomes:UP000191612}.
FT   DOMAIN          532..612
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   968 AA;  105389 MW;  7209EA695FAA7B38 CRC64;
     MTIVHRLDEV ALRYPDHVAL KPHDGSPLTY AEVQRRINVI ANELLRNGVG TGTRVGVFQS
     PSAAWICSLI AILRVGGAYI PLDKKVGINR LAIIMKETQA SVVLVDTNSI SDYALLHTTA
     KPIDVWGLND FTARAVRNMA IPSQTAVIMY TSGSTGVPKG IMIAHSAYVH HVQSCSEVWK
     LKQGSEIILH QSSYAWDASL WQIMVSLCSG ATLVIASDLT RGDPVAITRL IASENVTCTL
     ATPTEYLAWV RHGRSHLSNS RLSTAVCGGE FMSSGLIQEI KNLHRPDLKL INAYGPAEIS
     VACSGSEVPY NLLDSTSTSP APALYTLPNY SVYIVDENLK PVPIGVPGEV VVGGAGVAQG
     YLDGTKTTER FSNDRYASKL FQERNWTTIY RTGDRGKLNR NGGLILLGRM DGDNQIKLRG
     IRINFEEIET TIVSYSAGAI TQAVVSVRSD ATDSATDQFL VAFAIMVPTH DSENALQFLA
     RLSQELPLPH HMRPAAIIPV ENIPQNTSGK TDRAAVSALP IPLISSKLPD DSTLTAFEQS
     LRQLWQQALP RELSSFHSID SLSDFFHVGG SSLALVNLQA LIKENLGASM ALYQLFEAST
     LRGMAARIQD ISRPALELDV NWDTEVEIAS DLTSSLNYSD THIIASGVKT VVLTGATGFL
     GKEILRRLIE DEKVSSIHCL AVRKRSLDLP ELFAHPKVHL HFGDLGAPQL GLSESDTRSI
     FSCADIVIHN GADVSFMKAY RTLKLINVAS TKELVKLALP RRIPFHFVSS AGVARLAGQE
     SFGETSVSSY PPPSRPTDGY IAAKWVSEVY LERINRQFGL PVWIHRPSSI TGTDAPELDL
     MGNVMRFTKT TQKVPDSSSW SGVFDLISVQ SAASQLLEAV HQSSVTELAI GSVTYLYESG
     ETKIGRDEIM PLMESGSGQQ FQIVSLDEWV NAAEQAGMSV LLGEYLRRAS DGQVLLPRLI
     KAGFSEDE
//