ID A0A1V6QDP8_9EURO Unreviewed; 856 AA.
AC A0A1V6QDP8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Homeobox domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENSOL_c080G04029 {ECO:0000313|EMBL:OQD87331.1};
OS Penicillium solitum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60172 {ECO:0000313|EMBL:OQD87331.1, ECO:0000313|Proteomes:UP000191612};
RN [1] {ECO:0000313|Proteomes:UP000191612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29525 {ECO:0000313|Proteomes:UP000191612};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD87331.1}.
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DR EMBL; MDYO01000080; OQD87331.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6QDP8; -.
DR STRING; 60172.A0A1V6QDP8; -.
DR OrthoDB; 450547at2759; -.
DR Proteomes; UP000191612; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR PANTHER; PTHR11850:SF383; ZN(II)2CYS6 TRANSCRIPTION FACTOR AND HOMEOBOX DOMAIN TRANSCRIPTION FACTOR (EUROFUNG); 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000191612};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 166..229
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 380..403
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DNA_BIND 168..230
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 223..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 15..42
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 301..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 94217 MW; E431638F54B240FF CRC64;
MEYFDFEGAS SAHGSNQLDD DVASIDIELD EAEEQAANFN SLVHDQTLGF SNNPVPEMSE
VNVSQAIDPV DPDGVYPMFR AQEPCDFCGR MGLDCFVAKR GKLNYGCTCC ISLWRECSFT
HAKTPGKFLQ TLHSVSENAH VPTGSLTGKK ALKSVSYNTY PNDPDSRSQK TGARFSRKAI
SILKSWLRDH NENPYPTEQE RDDLKQHTGL TRTQIANWLA NARRRGKVRA SPGSSSPVPG
AVDIPVKQSV NTSLMTPLER WKYSPPENEP ATISDITRAL ANPPFDPSRP RRAPSGHVRP
RRPGSSNNES SHASSEHKLC TASASSFDSS ISDLSFASAF SHRSSLSFGS MDRKERRRRR
KASVPVNTLA HSKAKSARPF QCTFCTDSFP AKYDWQRHEK SMHLILDKWT CSPDGGTIEQ
NGIPHCVFCL AANPDDEHLE THNFISCQEK TVQERTFYRK DHLNQHLRLM HNAKFQPCME
KWQSSITDIK SRCGFCGSVF QTWKDRVDHL AGHFKNGASM AQWQGDWGFD PQIQARVENA
IPPYMIDYEW RSPDPWATEQ AKGDGSTLRL PVPTDVNCYN RLSHELTTYI HNQKAQGLVP
SDQMIQAEAR RVIYGCDDPW NQTCADNVVW LGVLKRDCGL QTQVNNDSIQ FADLGMQPPF
AINGGLRAAP REINVLARAV CQGAPIHSPA ISSPSMRSHG FPGTGFSSAG PSRPGSLSGS
YAGSAGMMSA GPDPSFSVDW ASSLPTTASV PGESTADPLV QMGFDPEFLQ RLNDSYGEIN
SDDLEGLHLD GADGQKGPEQ QGWPNRSLLG QPIPPSHMGE VSASDPVAVF NSKADHPPAS
NATHDDVPGY FGNGNF
//
