ID A0A1V6QHG8_9EURO Unreviewed; 625 AA.
AC A0A1V6QHG8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Cytochrome b5 heme-binding domain-containing protein {ECO:0000259|PROSITE:PS50255};
GN ORFNames=PENANT_c003G00965 {ECO:0000313|EMBL:OQD88645.1};
OS Penicillium antarcticum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=416450 {ECO:0000313|EMBL:OQD88645.1, ECO:0000313|Proteomes:UP000191672};
RN [1] {ECO:0000313|Proteomes:UP000191672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 31811 {ECO:0000313|Proteomes:UP000191672};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD88645.1}.
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DR EMBL; MDYN01000003; OQD88645.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6QHG8; -.
DR STRING; 416450.A0A1V6QHG8; -.
DR OrthoDB; 1605658at2759; -.
DR Proteomes; UP000191672; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010960; Flavocytochrome_c.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01813; flavo_cyto_c; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR PANTHER; PTHR43400:SF8; HYPOTHETICAL FUMARATE REDUCTASE (EUROFUNG); 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000191672}.
FT DOMAIN 541..617
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
SQ SEQUENCE 625 AA; 67113 MW; EBD5E9847B749C58 CRC64;
MAPQVIVVGG GLSGLSAAHT VYLNGGNVVV LDKQAFFGGN STKATSGING ALTRTQTDLG
IQDSVKQFYD DTLKSARDKA RPDLIKVLTY KSAAAVEWLQ DVFNLDLTLV SRLGGHSQPR
THRGHDAKFP GMAITYALMQ RLEELADKEP GRVQIIKKAN VTSINKSGNN VTGVSYTLNG
EPKSVDGIVV LATGGYAADF GDTSLLKQHR PDTFGLSSTN GTHATGDGQK MLMAIGANGI
DMDKVQVHPT GLVDPKDPQA KFKFLAAEAL RGEGGLLLNS DGQRFSDELG HRDYVSGQMW
KEKEKGKWPI RLILNSKASN VLDFHTRHYS GRGLMKKMSG KQLVEEIGCG EAALKKTFDD
YNQIADGKKK DPWNKRFFHN FPFTLDDEFH VALMEPVLHF TMGGIEINEH AQVLNGEQKP
FEGLYACGEL AGGVHGANRL GGSSLLGCVV YGRVAGDSAC QHLFQKLITS GGSASSRLGQ
ISLHIDPNTP GKVSVEWGAA AGGNLPTLAA APADASATTA AAAAPEQKAA KPDPANFKIP
ETEYTMEEVA KHNTKEDLWI AVKGIVLDVT NWLDEHPGGA NALFNFMGRD ATEEFAMLHD
DEVIPKYAGH TVIGRIKGQT PSLDI
//
