ID A0A1V6QST8_9EURO Unreviewed; 902 AA.
AC A0A1V6QST8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Alpha/beta hydrolase fold-3 domain-containing protein {ECO:0000259|Pfam:PF07859};
GN ORFNames=PENSOL_c043G11337 {ECO:0000313|EMBL:OQD92283.1};
OS Penicillium solitum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60172 {ECO:0000313|EMBL:OQD92283.1, ECO:0000313|Proteomes:UP000191612};
RN [1] {ECO:0000313|Proteomes:UP000191612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29525 {ECO:0000313|Proteomes:UP000191612};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD92283.1}.
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DR EMBL; MDYO01000043; OQD92283.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6QST8; -.
DR STRING; 60172.A0A1V6QST8; -.
DR OrthoDB; 1943592at2759; -.
DR Proteomes; UP000191612; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR InterPro; IPR002168; Lipase_GDXG_HIS_AS.
DR InterPro; IPR033140; Lipase_GDXG_put_SER_AS.
DR PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR PANTHER; PTHR48081:SF35; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR Pfam; PF07859; Abhydrolase_3; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS01173; LIPASE_GDXG_HIS; 1.
DR PROSITE; PS01174; LIPASE_GDXG_SER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000191612}.
FT DOMAIN 147..261
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT REGION 507..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..760
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 887..902
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 220
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10038"
SQ SEQUENCE 902 AA; 99385 MW; AEFB65DD144DFDFD CRC64;
MPLHTVALGV ALTPTVLHTL ISHYLHRKSL HNKPTVHVTY DEGIQIVRQF LFYASKHPVE
DLQAFTRQWA PSPHWVRTET ITIPDTFLSS AADAVTKQLG PKGVIRVGGE KWWQWRGPSE
ELKGEWIEMR NHYNQTEGAG GHCNRVMLYI HGGAYFFGSV DTHRYMMQRH ARKLKGRVFA
PEYRLSPQFP FPCGLHDCMA AYLWLLNSYE PKEIILAGDS AGGGLALSML VIMRDQGIPL
PAGAILISPW VDLTHSFPSI VEDNPGDYVP AYGFRHKPSP AWPPPNADDI LEMKRLSRQP
IVNAEDVKKA IPQPNSTAEE TAIRGYTVHE NGPPLAEHAY PGLQQAPNPA SLHAEPDNIH
VVLDGKTVEL KDQIQLYTTN QLMSHPLVSP VLQPSLGGLP PLQILSGGGE TLRDEQFYIA
HKAANPTAYP PSDAYLDEND PTRETLNKYE PTYVQLQVWD NLCHVAPTLS FTRPAKYMFR
SISQFGSWAL ARAQNGEVEI VDDSALSAVS SNSSEDEDVP GPRTALNSPP DAPGPSSVGK
AGDPLPAFHQ YMIRQRIDKR GHVFPLDPSS SYPVLEIPPA EVGAINPLLI RMWLDAKKEW
DIRFAKEKLR IQSRRLKELA HGFQDFDGEC PPPSSLAARR AAPGVLPKRH AKKNYGMMMW
SGWGSRHDER RMEMEKRAEE SGRRSTRVST DAGQAGAWSS TPATHPQPQK VSDKDLTDTK
SQSNGYTAVS PDKRERPRNG DSSIGRTSTD PETFSRPLSQ KSAGPILILP EVNNNKFTDE
NASTRALFHA AGSLPMKSDL SLAHSRYRPS SAAGSAAGRS EMLSDTASTV GGDKDSVAYM
NMAPDTASTR AVRSARGVIA PIMAGENGRR STDTLSVFSA AGRDSMSHRP EVLDREGSKT
AE
//
