ID A0A1V6R710_9EURO Unreviewed; 545 AA.
AC A0A1V6R710;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=PENSOL_c013G03290 {ECO:0000313|EMBL:OQD97111.1};
OS Penicillium solitum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60172 {ECO:0000313|EMBL:OQD97111.1, ECO:0000313|Proteomes:UP000191612};
RN [1] {ECO:0000313|Proteomes:UP000191612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29525 {ECO:0000313|Proteomes:UP000191612};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD97111.1}.
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DR EMBL; MDYO01000013; OQD97111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6R710; -.
DR STRING; 60172.A0A1V6R710; -.
DR OrthoDB; 3377831at2759; -.
DR Proteomes; UP000191612; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF423; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000191612};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 24..545
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5011828611"
FT DOMAIN 37..388
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 397..515
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 545 AA; 58927 MW; C640E6412891A0DD CRC64;
MKACWNLIGS VILLAMCLPA VWGQQCLDHP EMHIGGSVET SSGLVEGHAA PRRPAVSEYL
GIPYASPPIG DLRFAAPVAY DSNGTIQANA YSPCVYYTLT IMIYLTRVSD CPANAGSVPD
YPGFTPQAPQ IVKSFTQALG TSQSEDCLFL NVWTRPTVSK LKPVLLWFHG GRFTGGGANN
PYYDGQALAD EHEVVVVTIN YRLNILGFSG APDLPQNVGL LDQRMAVEWA HRNIAAFGGD
PERISIFGQS AGGSAVDYYS QAWADEPLVA GFISHSGTSL SFVPNTAEES ASYFYTASEL
LGCGDQTSDP EEVVKCVRQK PYTDVVKAGG KVPPAPSPAT PQAVFHPTVD GVTVFGNYTE
RSAAGKFARL PYLINSNHYE PGYYRISAFN ANISLSDSAW QSFNDAAFTC PSGASARYRV
DNGVPVWQSH YFGDWDNLRL YPNSGSYHGA DLPMVFGTGE HVSGIPNSDR ENEFARYMAS
AWVAFASDPQ EGLTKFGWPR YNPNEKTLVG LAYKDGYNSQ LLRPEDVEQG CAALKGDSTP
GKGAF
//
