ID A0A1V6R8U1_9EURO Unreviewed; 536 AA.
AC A0A1V6R8U1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=PENSOL_c011G12051 {ECO:0000313|EMBL:OQD97626.1};
OS Penicillium solitum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60172 {ECO:0000313|EMBL:OQD97626.1, ECO:0000313|Proteomes:UP000191612};
RN [1] {ECO:0000313|Proteomes:UP000191612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29525 {ECO:0000313|Proteomes:UP000191612};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD97626.1}.
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DR EMBL; MDYO01000011; OQD97626.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6R8U1; -.
DR STRING; 60172.A0A1V6R8U1; -.
DR OrthoDB; 1927251at2759; -.
DR Proteomes; UP000191612; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF362; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000191612};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 24..536
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5011820176"
FT DOMAIN 32..492
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 536 AA; 57987 MW; B04159E075299FC9 CRC64;
MGFFRTLSLT ATATAMALVV AEAHVCRSQS TSPSVSVEQG VVKGFFQNDT SVFLGIPFAE
TTAGENRWKA PNPISSFPNG QLEATAYGPS CAQVMSGTAI TDQSEDCLSL NIWTPGKGAN
LPVFVYIYGG AMVTGGSSNA QWQGFNFARN DVIYVNFNYR ESIYASPNAP ELQGESQNFG
VLDVELAMEW IHKNIEAFGG DKSRIVLGGH SSGGVHVDHY LWNHPDTFLA GAIEMSANAQ
SGPAIAPAGV ALKQVVQDML DAGVTLACTA ENYTLDCLRA ADTYAFQTTY FNSTSNTWFS
PVIDEITRFS NYTDRFVKGD YATSVPLIVG NSDQEGEIFG YVYGSENTNF SSWIRTFDAD
IAFVPADQLL AAYDEADYAS VSLMSGASYG DARFLCATDA LLDLRAAKQP TWIYRWFGDY
SNVLPIPNLG PSHGSEVPFF HGGNECFSLL DGVTDAEQKL ADYLNARFVA FVKNPTAGPG
WEKAQPVNGP LARLGVPGHE EEIVTSTTGV YNGRCQKVYK PNYPNYPVVL NPVLLA
//
