ID A0A1V6R9M4_9EURO Unreviewed; 1370 AA.
AC A0A1V6R9M4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=CAP-Gly domain-containing protein {ECO:0000259|PROSITE:PS50245};
GN ORFNames=PENVUL_c077G09233 {ECO:0000313|EMBL:OQD97892.1};
OS Penicillium vulpinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=29845 {ECO:0000313|EMBL:OQD97892.1, ECO:0000313|Proteomes:UP000191518};
RN [1] {ECO:0000313|Proteomes:UP000191518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00011010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD97892.1}.
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DR EMBL; MDYP01000077; OQD97892.1; -; Genomic_DNA.
DR STRING; 29845.A0A1V6R9M4; -.
DR OrthoDB; 9423at2759; -.
DR Proteomes; UP000191518; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR022157; Dynactin.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12455; Dynactin; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000191518}.
FT DOMAIN 26..68
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 78..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1034..1181
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 78..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1370 AA; 153310 MW; 993284F5F643755B CRC64;
MSGQALSIGT VIELPDGRQA TVRFIGITHF ADGQWIGLEL DEPTGKNDGA VQGERYFDCG
PGHGMFVRPT VVGKIVQPQP ESKQTTKPAT SAAGSKAQPK PGISTGMRKQ TGVPPTAARR
QSTNAASTPT PAPKGLAARS ALRSPTKSPT KQLATAAGPA IRPSIGSTSR TSTVASNRPR
LAPSNRSSLG PSPTQHTVSR GSRPSVSGPA GRASRPGSQS TVTSPTAGLT KRPSLRQVSN
TKASDGGDMG MSGRSGDPTD TESPDPEGEG VQDGGTTAPK ATRQPMATTR LAASRPGAPL
SASQRQGQSA AVNRELEELN AKLKVMEKKR ADDKEKLKTL EQLQAERDKF ETIIQKLQAK
YQPQQMEVTE LRKKLKELET RSDDVERMQA EHESLMEMAT LDREMAEETA EAFKHECAAL
RSKMDELSLE VEVLREENEE YSQETTPEDR TTHGWLQMEK TNERLREALI RLRDMTQQQE
ADLKAQIKEL EDDLEEYATI KSDYEAAKER ILVAEANVDD LKQQLETALG AEEMIEELAD
KNMRYQDEIN ELKAAIEDLE SLKEISDEME YTHIETEKQL QEEIEYREGV FSDQCRKITQ
QDEVIEDLEY TLTRFRDLVT NLQCDLDDMR TTKQVSEAET TENAMRHRQM QDLNMKLQAN
QSKALTKSID VELARMEAEE NAQHLSMVKL YLPEYFEGER NSIQALLRFK RVAFKANVMS
STLQEKGSEH SVLSNEEIFQ AHVVLEYLMW ISNVCDRFVN YITACSPEQF GGIKIAMFEM
EPVERMLNFW IEPLKKDEVN LAKLAVELQR SIALLAHLAE TLLPSSLEMF ADELCMRAHL
SQLYIEHSAG AISRVKLIIS SKMLAAAEGD EENLIALNKL DAFTPQARGY KVAMGKISRC
LDDLRSRSLA LPREAEEPFK KIENETKQLS ELARKIGESL VILTSDEGRT EQFSPEEILD
CMLQAAVAFT SSSDTPDESN DPVSLLFTRL REVGDQFEEL DSISSDLSRT TEFERAAYPW
IARAAELKSN KMTSPDADEE IRQLRNEIHE ASAALGVKDN TLEEQGLKIE HLESRMREAS
KKAAMVKDLE AKIEEIQAAA SELEKIVEQQ KKELQTAEAE RDDFMARLER MKRMSGTAGL
TTTGNGVAIA TEASLAAMDE NESLRAEVES LQAAVRFLRE ENRRSNILDP YSVQRSTEMH
AWLDAPLVRA NPTPEQEKIQ RTALESRDVM NHLLKLTKES RVTDLKSTMA AQASDDNDSN
NAGRTVWRPS RTRLRYQVLQ QRENFEHWAE WRDEIVNHER EQDRLVAAKQ ERAMRDRVSR
HSHKASVEFP QGLGHGMMGR AWQILGMQKH RKTGSISTPA PDGVEIVATD
//
