ID A0A1V6RBA6_9EURO Unreviewed; 488 AA.
AC A0A1V6RBA6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=PENVUL_c070G06835 {ECO:0000313|EMBL:OQD98597.1};
OS Penicillium vulpinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=29845 {ECO:0000313|EMBL:OQD98597.1, ECO:0000313|Proteomes:UP000191518};
RN [1] {ECO:0000313|Proteomes:UP000191518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD98597.1}.
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DR EMBL; MDYP01000070; OQD98597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6RBA6; -.
DR STRING; 29845.A0A1V6RBA6; -.
DR OrthoDB; 4829785at2759; -.
DR Proteomes; UP000191518; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF360; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000191518};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 21..488
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5011821848"
FT DOMAIN 46..467
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 488 AA; 53947 MW; AB428110F0649560 CRC64;
MAIKTIIILI GGLFGGLLSA LPSPSMPRFP FGPLCVGVGE STSDCLAEDC LFINVWRPTN
ASADSNFPVW LFIQGGGYAN NANGNYNGSE VVQQSGNNIV FVNFNYRVGV LGFLASEHVR
KNGDLNAGLL DQRKALHWVQ KHIRKFGGNP DHVVIHGDSA GAGSVAYHLT AYGKRNTALF
VGAVAESPFW PTQRTVAQME FQYDRFVKNV SCDNTTDSLE CLRSVDIKTI QKFNLDNPFP
GGSPTPVPRW YFLPVVDGNV IHDQLYNLFN EGKFVHVPLL VGDETNEGTD FAYNASNKPE
VAQFRKNNYP GLSRGQLNAI NKAYEHAEPL PRHAACFALA AGAYGDSTFT CPGNFMAAAM
AKSFSPHRVW NYRYNVRDAT KIANGMGVPH VFDLPAIFGV GETNEPTYSY ASFNAKIVTI
TMDYYLSFIK ALNPNIYRYK DSPEWQAWGI GAGQRLKLQT NSTEMELIPR LEVERCSMWK
DFAAAMQQ
//
