ID   A0A1V6RF62_9EURO        Unreviewed;       332 AA.
AC   A0A1V6RF62;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=PENVUL_c057G06996 {ECO:0000313|EMBL:OQE00144.1};
OS   Penicillium vulpinum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=29845 {ECO:0000313|EMBL:OQE00144.1, ECO:0000313|Proteomes:UP000191518};
RN   [1] {ECO:0000313|Proteomes:UP000191518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE00144.1}.
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DR   EMBL; MDYP01000057; OQE00144.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6RF62; -.
DR   STRING; 29845.A0A1V6RF62; -.
DR   OrthoDB; 1788094at2759; -.
DR   Proteomes; UP000191518; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd05289; MDR_like_2; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR44013:SF5; OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01290)-RELATED; 1.
DR   PANTHER; PTHR44013; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000191518}.
FT   DOMAIN          9..326
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   332 AA;  35940 MW;  A21D74A45555EEC6 CRC64;
     MRSIIQQTAS SKALTLTSTR LPIPNHAQKE HLIQVKACSP CAGELLWPKN FPPPTARTLI
     PCPDMAGIVV SAPEDSPFQS GDEVYARTNY VRPGNACEYS IAVTDELAHK PKGLSWVQAA
     AVPVSAETAW QVLFVHALAT GDVEEMDLEA AKLAWAGKRV LVTAASGGVG IWLVQLATLL
     GAEVVGTCGS GNVELVRSLG AKEVLDYRVA DLREWATQSP SNKVDVVIDC IGGKALGDAW
     WTVKDGGVVL SIYQPPLQVC PEGFEGESVR DLFFVMQPVR RQLEEISKLV EKGVCRGLVD
     SVWPLEQYEE AFKRLDGGHT KGKIVFDLSL NH
//