ID A0A1V6RQK2_9EURO Unreviewed; 711 AA.
AC A0A1V6RQK2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=polynucleotide adenylyltransferase {ECO:0000256|ARBA:ARBA00012388};
DE EC=2.7.7.19 {ECO:0000256|ARBA:ARBA00012388};
GN ORFNames=PENSOL_c001G06634 {ECO:0000313|EMBL:OQE03693.1};
OS Penicillium solitum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60172 {ECO:0000313|EMBL:OQE03693.1, ECO:0000313|Proteomes:UP000191612};
RN [1] {ECO:0000313|Proteomes:UP000191612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29525 {ECO:0000313|Proteomes:UP000191612};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B-like family.
CC {ECO:0000256|ARBA:ARBA00008593}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE03693.1}.
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DR EMBL; MDYO01000001; OQE03693.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6RQK2; -.
DR STRING; 60172.A0A1V6RQK2; -.
DR OrthoDB; 21395at2759; -.
DR Proteomes; UP000191612; Unassembled WGS sequence.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092:SF15; INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED; 1.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000191612}.
FT DOMAIN 279..379
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 449..502
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 1..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..120
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..604
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..673
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 79575 MW; E0569AF424A99C99 CRC64;
MPPSAPFQFR GSSNYRGSRP NPRHEFTFRY QKPATSDRPL LSSKRESTPE RLEGETKPGL
KFAELSTLSD SEEAEMDMSD DSDGERPRKR RALALDGPQE TAPAPPAPKW SNPDPYTALP
PPAETTNKRV DVVKLIRKAR LDIAAKTDET DAVKQNSDFI SLGMSFEPEI PQSNAPDNAP
RGPKAQEVLD PAIASRKRTR EDEIKGYSRK TGKPASRFNY DGSVIDQWKP LSQETGTPWF
EGTPVSLHVG TQLHNEILSF YHWAKPQEFE HIVRADLVNR LETAFQQRYH NVSIRAFGSF
ASGLYLPTAD IDLVLLSHTF LRTGVRTFGE RKGQIYAFSA FLKSTNIAVP NSIECIASAR
VPILKYVDKL TGLRVDLSFD NDSGLIANET FQKWKTQYPM MPVILAVIKQ FLLIRGLNEV
PTGGLGGFSI TCLVTSILQH LPQGHMQPNL GTILLDFFNF YGKQFTYDKL AIRMDPPGFF
NKGYYFGNPD RLTIEDPNNR DNDISGGTKE IGLIFRAFSN AHTALRNRME YLALVQGSNK
SILEPIIAAN FDEYIEQRFQ LRQVFMTEER FARYRESPPP PPPPGSPPAN RASPPPPPPV
DGSRSPLSAP SAQRPAKKPK TKSKGTKSEP EDISSDEAPG PDAKSAKARK GETRRQLCQE
RAARLKRLRP DLKKLPNTLS LRQARRHAGY ETDEQMNADL DSREQKLLAS A
//
