ID   A0A1V6RTN6_9EURO        Unreviewed;       424 AA.
AC   A0A1V6RTN6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Saccharopine dehydrogenase NADP binding domain-containing protein {ECO:0000259|Pfam:PF03435};
GN   ORFNames=PENVUL_c030G08000 {ECO:0000313|EMBL:OQE04773.1};
OS   Penicillium vulpinum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=29845 {ECO:0000313|EMBL:OQE04773.1, ECO:0000313|Proteomes:UP000191518};
RN   [1] {ECO:0000313|Proteomes:UP000191518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE04773.1}.
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DR   EMBL; MDYP01000030; OQE04773.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6RTN6; -.
DR   OrthoDB; 5479972at2759; -.
DR   Proteomes; UP000191518; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000191518};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        289..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..150
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   424 AA;  46417 MW;  71AD3702376D95B0 CRC64;
     MYDIVLFGAT GFTGKLCAHF ISQNYPLTTQ WCIAGRSLSR LEAVVDELKQ LCPDRVAPGM
     TQPLIMIIQV GPDTHKDIEI IELNPSSLNP LIQRTRVVIN GIGPFHRFSS PIVSACATLG
     THYVDFTTEI PWIQEMIQKY GEFARQSGSL LIPGLSTSTP SDILAWLIAN KMQEAYSTDT
     AGVISSGKLD IKAMSAGSLN TVLDTFETYG SGWYLYGDSS ILSAPFRKQT MSPWITRILG
     YRHTQELGTL ATSFTGPGNQ EVVYRSASRK PDLYGPDFHF EEYLPANGVI AAVSVHLLTK
     FLLVLLSIPF IRLLIRKLAA RLDSAPDVKQ LRQVERAEFR AIGSGSGDAK PRVWASFVRE
     GALYELTALV TCIGARVLLE QKISADRAGK DARGHGGVVT PSFLGMEYVD QLKDAGIEIE
     GGLL
//