ID   A0A1V6S3Y5_9EURO        Unreviewed;       575 AA.
AC   A0A1V6S3Y5;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN   ORFNames=PENVUL_c008G02535 {ECO:0000313|EMBL:OQE08765.1};
OS   Penicillium vulpinum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=29845 {ECO:0000313|EMBL:OQE08765.1, ECO:0000313|Proteomes:UP000191518};
RN   [1] {ECO:0000313|Proteomes:UP000191518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE08765.1}.
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DR   EMBL; MDYP01000008; OQE08765.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6S3Y5; -.
DR   STRING; 29845.A0A1V6S3Y5; -.
DR   OrthoDB; 4403at2759; -.
DR   Proteomes; UP000191518; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF39; ADENOSINE DEAMINASE 2; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000191518}.
FT   DOMAIN          233..529
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   575 AA;  66025 MW;  D7C422C2273EA045 CRC64;
     MANTENEWEL EEGIPQVGDP FIQQYLKGRD ALIMEEQKRR HDANLRKSLS PIAARAAKIV
     SQIRAQEQNE VWTHGLDEAA AHQSDEILYP GVMFNLAKGR MEKTKLWKIV EKMPKGSLLH
     AHMDAMFDIE FLIDQAFSTP GIHMFAPKPL ITAKDYEEAP VYFRYSPQPL EISEEKPSIW
     SETYEASSLI PIQKAASSFP KGGEKGFREW LNNRCILLPE HSYHHHHGVD AIWSIFTNTF
     PIVDSILMYE PIFRACFRRL LGQLAEDGIR YVEFRIGFVF EFRKEGNNKP EEDYFEWCRV
     VEDVLTQFKQ TDEGKDFYDA RIIWTTLRWF SNELIVKSMK QCIETKQEFP DLISGFDLVG
     QEDNGRPLVD LVPVLFWFRK QCAEEEVDIP FFFHAGECLG DGDVTDHNLF DAILLGTRRI
     GHGFSLYKHP LLIDLVKEKK ILVECCPISN EVLRLASSIK SHPLPALLSR GVPVSLCNDD
     PAILGHGRNG LTHDFWQALQ GLENVDLVGL SMMAQNSIRW SCYEDQSTAE WKAGIQNGVT
     GKGLKSERLQ HFALDFEKFC EWIVLEFAEF DAEDN
//