ID A0A1V6S5C6_9EURO Unreviewed; 1297 AA.
AC A0A1V6S5C6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Rad50/SbcC-type AAA domain-containing protein {ECO:0000259|Pfam:PF13476};
GN ORFNames=PENVUL_c008G06293 {ECO:0000313|EMBL:OQE08944.1};
OS Penicillium vulpinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=29845 {ECO:0000313|EMBL:OQE08944.1, ECO:0000313|Proteomes:UP000191518};
RN [1] {ECO:0000313|Proteomes:UP000191518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE08944.1}.
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DR EMBL; MDYP01000008; OQE08944.1; -; Genomic_DNA.
DR STRING; 29845.A0A1V6S5C6; -.
DR OrthoDB; 5477220at2759; -.
DR Proteomes; UP000191518; Unassembled WGS sequence.
DR GO; GO:0030870; C:Mre11 complex; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR004584; Rad50_eukaryotes.
DR NCBIfam; TIGR00606; rad50; 1.
DR PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR PANTHER; PTHR18867; RAD50; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000191518};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 8..241
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 200..251
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 389..523
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 576..631
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 706..761
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 789..1045
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1297 AA; 149382 MW; 4D7B5B067842D484 CRC64;
MLTAFQVVRS FDNTRSETIQ FHTPLTLIVG YNGSGKTTII ECLKYATTGD LPPNSKGGAF
IHDPKLCGEK EVLAQVKLSF KATSGAKMVA TRSLQLTVKK TTRQQKTLEG QLLMVKNGER
TAISSRVAEL DQIMPQYLGV SKAVLDSVIF CHQDESLWPM SEPSVLKKRF DEIFEAMKYT
KAIDNIKALR KKQNEELGKY KIMEQHAKED KDKADRAEKR SVKLQDEIEA LREEAQQMSQ
EMRRVAELAD KAWTQSESYA QILGALEGKR IEAKSIQTTI DNLKRHLVEL DDSDEWLEST
LEQFETKQIQ YQQQEESQKE HYMETKEQIE QTRHRLGLKQ AEHGKFENDK ANFERQSQRR
QKMINEIARA NNIRGLDEKM DQSEIDTFMQ KIKRLLRDQN QSLDRVRREA QKELREVQDI
LNEIGQKKSA LQETKNAAKR QIAANDKEAT TYQKKLNEIE VDEGFQAALE SKVEDITSKL
EHAKERAKTA SWDQDIQDTN AEIRRLEDES SRLNTELIDS TKKAGDLARL DHLKKESKDR
ERSLQTMKGA HGDRLEKVVG PDWKPETLER GFQQALDSES KQVADAERER DGVSRELEHV
EFKLKTAKKN LKQRQKELDE CMKEIHEAVD TEPSEYPEIV KERQAQYDLA RKDADQYAGM
GEYLTKCLDA AKRTKLCRTC QRSFKNEAEL QTFTKKLDAL VKKAGLDAED ETLKSLEEDL
ETARAASASY DTWVRLSETV IPELEQEEQE FETRRDQLLE KLETQDGKVS EKRESKREVE
GLAKTVSTIA RYDIEIKAIK SQIQELSANH QDASTARTLE DIQEEIASIN EKSRELKKTL
TKMTNEKEKT RSEINKLELE FRDVKSNLDN AKFQLEKKAD LTVRMEESKK LNNQQRDAIE
KADRDIESLT PELLQAQARY DDISQRADER ERDLQHEISR LSENIHQLDL ANDDINSYNQ
RGGPGQLERS KQELQEIEAE IGKLEAEQSA ITREINKISA QLKDSENTKR QYSDNLTYRQ
ATRSLNTVVE EVEQLEAQNA EVDRGRFKQE SERWTREHNA LAAKQASKMG EMKSKDDQLM
QLLADWNTDY KDASSKYKES HIKVETTKAA VEDLARYGGA LDKAIMQYHG LKMAEINAIA
GELWQKTYRG TDVDTILIRS DNENAKGNRS YNYRVCMVKS GAEMDMRGRC SAGQKVLASI
IIRLALAECF GVNCGLIALD EPTTNLDRDN IRSLAESLHD IIRTRQQQAN FQLIVITHDE
EFLRHMKCGD FSDYYYRVSR NERQKSIIER QSIAEVM
//
