ID A0A1V6S5Q7_9EURO Unreviewed; 1383 AA.
AC A0A1V6S5Q7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=PENVUL_c007G02956 {ECO:0000313|EMBL:OQE09059.1};
OS Penicillium vulpinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=29845 {ECO:0000313|EMBL:OQE09059.1, ECO:0000313|Proteomes:UP000191518};
RN [1] {ECO:0000313|Proteomes:UP000191518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 29486 {ECO:0000313|Proteomes:UP000191518};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the putative lipase ROG1 family.
CC {ECO:0000256|ARBA:ARBA00007920}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE09059.1}.
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DR EMBL; MDYP01000007; OQE09059.1; -; Genomic_DNA.
DR STRING; 29845.A0A1V6S5Q7; -.
DR OrthoDB; 2551282at2759; -.
DR Proteomes; UP000191518; Unassembled WGS sequence.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007751; DUF676_lipase-like.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19848:SF8; E3 UBIQUITIN-PROTEIN LIGASE TRAF7; 1.
DR PANTHER; PTHR19848; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF05057; DUF676; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF00400; WD40; 8.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 9.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50837; NACHT; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 9.
DR PROSITE; PS50294; WD_REPEATS_REGION; 7.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000191518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 376..594
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 898..939
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 940..981
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 986..1022
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1023..1064
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1065..1097
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1107..1148
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1149..1181
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1191..1232
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1232..1273
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 1383 AA; 155056 MW; 8FC90F9B13C96A8A CRC64;
MQLLRRQREA VFQVKETGHN NPRAYSATDP ALPEYPPISH FIDGIKVLSN PPNATCDICF
IHGLTGDRER TWTAKGQSAP WPQSLLPQKL QQARILTYGY DAYVISKSKA SRNRLIDHAT
NLLADLTSDR ESCNASSRPL IFVVHSLGGL VCKKAILLSR NNPERHFQGV FDALKGVIFM
GTPHMGAWMA DWAKIPATAF GFVKSINISL LDVLQRNNQF LESIQRDFLA MVRQVRENGR
PLEITCFFEE LPTPKIGTIV TKDSASFDGY APRAIRADHQ HMVKFATVED PGFKRVLGEL
ERWTLAVDKL LLLNQTKDHY ALSVEDGACL RDLYTTDPRD DKKRIEKVKG GLLKDSYRWI
FENNDFKKWL YDQQGQLLWI KGDPGKGKTM LLCGIINELK STPQACVVFF FCQATDARIN
HASAVLRGLI YMLVAKQPKL MSHMRRQHDK TGKKGFEDAN AWETLSKIFI DILEDPLLQS
TYVIIDALDE CTADRNLLLE LIAQKSSVCT RIKWVVSSRN WHDIGEALEP ATKKATLWLE
LNEKSVAKAV TIFIQHKVRE LTEQKKYKAE VRDAISQHLF SNARGTFLWV ALVCLELAKG
ARWDARLLLT VFPPGLESLY ARMIDQIHKS PSAEICKRLL GVALVTYRPI TLGELLALVD
IPKDITINEQ SLNEVVEACG SFLTVREGVV FFVHQSAKDF LLQTASKKIF ARGIEAEHYT
ILFRSLQSFR TLRRDIYGLK SPGFPITQVR QPDPDPLAAV RYSCLYWVDH LLDGNAIDEL
REGGLVEGFL KQRYLFWLEA MSLMGYIPEA IAAMLKLNRF LQKLNKAHKL AERIRDASRF
IQYHGIAIEN SPLQVYFSSL IFSPTRSMIK SSYQSVKTKW LLKDPLMDDE WSPCLQILEG
HRAAVTSIAW SKDGNSLASG SSDTTIRIWD PSTGRCTSTL RGHKQVVVSI SWSPDGARLA
SGSLGRNVKI WDLPTRQCIS TLEVDSSVTS ISWSQNGRQL VIGSTSQPIT IWDQVTGEFT
WTLAGPTNPV CSIISSLDRS WLASKSDTTA IKIWDIATGR CTSTLTGHSS DVLDIAWSHN
GSRLASASVD MTIKIWDPAI RRCILTLEGH SSEVSCIAWS RDAKWIASGS FDGRVMIWNA
DTGQCISELE GHRDTVSSVS WSRDGSQVAS ASTDGTLKIW DPALKQGRSN LEGHNELVYS
MEWSRDGSQL ASGSHNGKVM IWNPATDQCM TLRGYNDAVF CIAWSRDGRQ LAIGSDVEMV
KIWDVATSKC VKTLAVRSGL SLQYDEVNVH YLHTDRGIFD LRSSALIPTS FGSLAPQPEQ
GVYAFNKDHT WITMRGENFL WIPSEYRTCC MALFAARATT TVAIGCLTGR VLFLTLPNNN
PIL
//
