ID A0A1V6SFS3_9EURO Unreviewed; 352 AA.
AC A0A1V6SFS3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN ORFNames=PENFLA_c061G07750 {ECO:0000313|EMBL:OQE12857.1};
OS Penicillium flavigenum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=254877 {ECO:0000313|EMBL:OQE12857.1, ECO:0000313|Proteomes:UP000191342};
RN [1] {ECO:0000313|Proteomes:UP000191342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 14082 {ECO:0000313|Proteomes:UP000191342};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE12857.1}.
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DR EMBL; MLQL01000061; OQE12857.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6SFS3; -.
DR STRING; 254877.A0A1V6SFS3; -.
DR OrthoDB; 1694166at2759; -.
DR Proteomes; UP000191342; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000191342}.
FT DOMAIN 7..253
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 352 AA; 39423 MW; A86EC16356615534 CRC64;
MTRNVSLVTG ASGFIASHVV QQLLETGDQV HATVRSTKNE KKIRHLLDMQ ERWPDKLSLF
EADLLVAGSF EVPMKNCSVV YHIASPFFIE NKISDGQKEV VEPALKGTEN VLDAVQKCET
VNLVVLTSSV AAIFGDNADV LEMKNKTLST EYFNTTSSVN HNSYPYSKVV AEKEAWKLYE
AQPIPRRWKL VAINPGLVLG PSLSPTSESG SLSLLDQLLR GQLFLGVPDF WFAIVDVREV
ATAHIRVARD PNSHGRYILA DKKTYSFVEL ARIIRSIAQS IKIPRNKLPD ALVRMSGPVL
GLSQKWLRLN LGISFDIDNR PSLDQLHIVY RPLEETLMDH YQSWKSAQTV LN
//
