ID A0A1V6SMB0_9EURO Unreviewed; 619 AA.
AC A0A1V6SMB0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=PENSTE_c032G08198 {ECO:0000313|EMBL:OQE14890.1};
OS Penicillium steckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=303698 {ECO:0000313|EMBL:OQE14890.1, ECO:0000313|Proteomes:UP000191285};
RN [1] {ECO:0000313|Proteomes:UP000191285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 24891 {ECO:0000313|Proteomes:UP000191285};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE14890.1}.
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DR EMBL; MLKD01000032; OQE14890.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6SMB0; -.
DR STRING; 303698.A0A1V6SMB0; -.
DR OrthoDB; 1387367at2759; -.
DR Proteomes; UP000191285; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000191285}.
FT DOMAIN 26..491
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 619 AA; 69453 MW; 5BC7CA585BCC2A77 CRC64;
MSPKLRLEQI PIVQLPTSSI PSHIQTVIGK RSVISDDIEE FRGIPYAHVP GRWEHSRLRD
RLPRDVFDAT ENGPRCPAQG KPDTRIFQSY LPYPDDRQDE FDCLNLFVVR PSKEALARNG
IDADTSQLPV LIWIHGGGFI DGSGTDPSSD PSRLVLRSLS NNTPFIAVSI NYRLGIFGFG
ASSDIISGQG NDSPIEGVNF GLYDQRLALM WVKRNIAAFG GDNTKITIMG HSAGGISCHL
HLLEAELGTQ RPLFRKADLM SGPLGGLELT SMSKADQRWE DLCQLWSVQA DSSVDRVDML
RRIPTKDLLN SVSDLHWVLF TLTVDGLTIR ESQLGCGISV HLGHNELSDE TKLPGEEVQV
LMSTAADEFR GFVLMANWDY TTFHSFFTSS YPSEAEAEKV LQTYGIVPTS SDEELFEAYS
QFISDATMMY KTYRASEFFK THRGKQALLR GQDPKRVGIQ NYHFEFGNPF SGPMQGIAHH
GVELVYAFGN FHDALQKADQ GILEGYVEPD QAHAEANIGE PSTNTEATTE YRKSNIDLSY
ELQDKLIQFV VEDCHETDQR AYIDNIVTFC NDRSVRVESW SHDEKWISKR MKLEALDRDY
DSMMTATRRL VGSVIGMEL
//
