ID A0A1V6SSC0_9EURO Unreviewed; 1216 AA.
AC A0A1V6SSC0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 22-FEB-2023, entry version 22.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=PENFLA_c026G06711 {ECO:0000313|EMBL:OQE16916.1};
OS Penicillium flavigenum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=254877 {ECO:0000313|EMBL:OQE16916.1, ECO:0000313|Proteomes:UP000191342};
RN [1] {ECO:0000313|Proteomes:UP000191342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 14082 {ECO:0000313|Proteomes:UP000191342};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE16916.1}.
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DR EMBL; MLQL01000026; OQE16916.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6SSC0; -.
DR STRING; 254877.A0A1V6SSC0; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000191342; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR Pfam; PF20168; PDS5; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000191342}.
FT DOMAIN 115..276
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1032..1192
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 176..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 854..884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1216 AA; 135986 MW; 2FDA188A792001CE CRC64;
MEDRIQFNIN ESLKYYLSDP ASIPTPDADP ELLDCESDPD QLSSALIDSV LNPIVDAVAE
NPEGLTRASL FDSLQFLLKC APVPSQVAHG GWRPPGHESD DPFHSCRYAT LLPAKYLSKL
LDLVVSGLSV EADIIHGDLE SDDQDAIQHH KQLLEMYGFL LQWALSAVEV KAAEKPTEAA
PVRRGGPKSK KSASSGQWDW TPQIQISMET MCKVMKLKLG RIFLTTSDRD TFITLFTRTI
YLVLESEQRV KSMAIRMHAF KVLCIAVKHH GQAFGAQTSI VQSLTYFEHL SEPMAEFLHI
LAEQYDYPQL SDEILKELGN KEFNSNDTRG PKSVSTFIIK LSELAPRLII KQMTLLAKQL
DSDAYTLRCA VIEVCGNLIS DLSRQEERSD NYKTQINAFF DVLEERFLDI NPYCRCRAIQ
VFMRICDLEQ KFPKRRHAAA ELAARSLEDK SSNVRRNAIK LLSKLVSTHP FSVMHGGLLS
YKEWTDRLDV VDAELNALRP PETPGFEAGD MTQVDPELLD DATQMPDDSP SKAPRMSEEE
KAIAVQKAAE QAATSELMTR LQLTRKYYNE AIRFIEVLHS GSTIVTQLLS SRNKSEVIEA
MDFFVVLDAY KVETARSGIR RMLRLIWTKG NSDEGKGVQT HLIDCYKGLF FDAPGSFSPN
DAANYIARNM ISLTFGATPA ELTCLEQLLS TMMKAGNVSE AVIAKLWQVY SIQKKEISRT
QRRGSIIVLG MLALADPEVV VKEIEAMLRI GLGSLGRADL VLAKYTCIAL RRMIPGRQAK
SKEVVGIPKL ASDHSVLVKL AAMLEIETAS KEWYGVAEHA LNAIYTLSKH PDVLCSDILR
RKTRFVFAPH LQQRPPSSHA SVNAEEEQQR PGTASTEGQE SKPKPASAAL SQLLYVVGHV
AIKQIVHLEL CELDFKRRKV EQEKNKAAAA PQEEDNAEGD ELDLIGGTTE DDFQDAMAHI
RERELLYGEN SLLAKFGPLV VEILANNNSY PDRDLQASAT LCLAKLMCVS AEYCEKNLPL
LITIMERSED PIVRSNAVIA LGDMAVCFNH LIDENTDFLY RRLNDDDDSV KRTCLMTLTF
LILAGQVKVK GQLGEMAKCL EDDDKKIADL ARMFFTELAT KDNAVYNHFV DMFSLLSAEP
NLDEASLRRI VKFLIGFVEK EKHARQLAEK LAARLPRCET ERQWNDVAYA LSLLPHKNEE
ITKTVSTGFK VVSAAA
//
