ID A0A1V6T2Y3_9EURO Unreviewed; 2674 AA.
AC A0A1V6T2Y3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN ORFNames=PENSTE_c013G09947 {ECO:0000313|EMBL:OQE20556.1};
OS Penicillium steckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=303698 {ECO:0000313|EMBL:OQE20556.1, ECO:0000313|Proteomes:UP000191285};
RN [1] {ECO:0000313|Proteomes:UP000191285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 24891 {ECO:0000313|Proteomes:UP000191285};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the GCN1 family.
CC {ECO:0000256|ARBA:ARBA00007366}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE20556.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MLKD01000013; OQE20556.1; -; Genomic_DNA.
DR STRING; 303698.A0A1V6T2Y3; -.
DR OrthoDB; 6844at2759; -.
DR Proteomes; UP000191285; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR022716; Gcn1_N.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR23346:SF7; EIF-2-ALPHA KINASE ACTIVATOR GCN1; 1.
DR PANTHER; PTHR23346; TRANSLATIONAL ACTIVATOR GCN1-RELATED; 1.
DR Pfam; PF12074; Gcn1_N; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SMART; SM01349; TOG; 2.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000191285};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1357..1579
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 1520..1558
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 1663..1877
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 1980..2017
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 2632..2653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2674 AA; 291230 MW; 1C84831E9452DA3A CRC64;
MDPIPWDQVK TGDLGALRVA LFSSSTSRRL RALQELRDKS GTEIPVEFHQ DVLALLFQTY
PLYVDRPSRQ AVQQCIRALL QTPNATESVQ YIAQRLKTEA VKPGLAAASA FVLLEWCCIV
LQQVSEDQAS PLTIVLDLIA VDAKALENCF AHTPRIPVKQ SALRVTRRAL RAVFSSPTWG
EDAVRQSVSQ LTTDSAAGNK NALFLGVIAG VCARLPARKP ILEESKKSIL DYYVKEIISS
KAVVPSHIAE GLSDFFASYV TSGDVATELV PPLEKSMLRA PEVILTGVIP PWSASLPDDI
DLSEVVQSRL SKHLLASMKS NNPAIRQGAA DSFGSLLSRC KTDALVLKIS SEIVGPLKSQ
KLTAPEHRVA YAQVIAAIPF SIDVSKEIVH GFGPLFSRES NEAALEEELK AFGKHLSFLI
QSTVKVSDDI VNTIVKGVAD KRVPFRKLWQ LNVGEVLWTA DIGSLKNPEV EPFVSKFLSK
MKDLFGEVAS NPLPSAQSGA LSSAYIFLAL FQRIADIEGT EKSTWEEKVS QSMTMGSKPS
FLLNSRAYSK LTTKAEMQWL VRSLAAVTSS PKFDAAEDAA KIAWAQSFIF TITVPTMPTS
LRENAVETLS SVHVKNVASI GGIVVNALWA WILSSRTQEK ESAAVFAGPG SERQLHHVLR
ALCPSSANKE ESEIIANLET QMIQILILSR PEMVPNASWI DLCLKAGIDP GNLVRAHQTE
CIEQLVNVNT DPVQSIVPDV NPAVWGAAAD LAFVAPEVMI PRLVDQIKED LNGDRLSKFS
ATDAAIARTP DGTTFVDVLS SKSKQPAFDK NTKDYDTLKW EEELKAQLAE KKGQKPKKLT
PEEQSKVKAQ LAKEADIRKE VLAEVKRIER GAGLIHGLAT GPANDAEGWI NSAVGCLLSL
SRAGAGLFVG DIVSQAYVTC ANELTSRLGH IRPFVGVATL RAIGKTNLPP SMELENLGEL
VTRILYKLRF TSEQRPLDIP SIAYVLPLLF LILSQNGIEE VKGEQEGEQV LLALDILSFH
TSLFNDTRLP RNEVLQHLLS AMQKYTQHYK LIKDILFNFC RCISPNINSE ELQTLLEGTI
VTDSSVRNSV LQVIDDEIDL TDLDFSEHIW LGCHDHVEEN VEIAETIWED NALEVDSSAF
AKISKYLDSK DSQLRGAAAR ALAHAVEFDK DQFTGIIAEL EAKYSEEIKP KAPEKDAYGM
PKKVDNADNW ESRSGIALAF NAMTSLFDGD QIIDFLQFLI ERGPLVDKNS SVRAQMAESG
KSVIAQRGQQ KVEDLMKLLE TVLETSDKAT QSSDLLNEAV VVLYGSLARH LKADDPRLQT
VIKKLLATLP TPSESVQSAV SECLPPLIRL SGPKTSEYVK EMLDQLLNVK SYATQRGAAY
GLAGIVSGKG VSTLREFRIM SMLTDALDNK KDPHQRQGAV LAYELFATVL GRTFEPYVIQ
IVPQLLAGFG DMSIDVRDAC LDASKACFQN LSSYGVKKIL PTLLDGLDDT QWRSQKGACE
LLGAMAYLDP QQLAVSLPAI IPPLTIVLND THKEVRNAAN RSLQRFGEVI GNPEVKSLVN
VLLKALSDPT KYTDEALDSL IKVSFVHYLD APSLALVVRI LERGLGDRSN TKRKSAQIIG
SLAHLTERKD LTTHLPIIIA GLNLAIVDPV PTTRATASKA MGSLIEKLGE DALPDLIPNL
MNTLKSDTGA GDRLGSAQAL AEVLAGLGTT RLEETLPTIL QNVSSSKAAV REGFMTLFIF
LPACFGTSFA NYLSKIIPPI LAGLADDIDS IRETSLRAGR LLVKNFATKA IDLLLPELER
GLADDSYRIR LSSVELVGDL LFSLTGVSGK AEADEEEEEA QQAGQSLLEV LGEERRDKVL
SALFICRCDT SGMVKSAAMA VWKALVASPR TLKDMLPTLA QLIIRRLGSS NMEQKVIASN
ALGDLIKKAG ESVLSTLLPL LEEGLQTSPD VDVKQGICIA LRELITSATP EGLEDYEKVL
ISTVRVALVD HDEDVREAAA EAFDALQQIL GKKAVDQVLP YLLHLLRNDD EAEQALSALL
TLLTEQTRAN IILPNLIPTL LTPPITAFNS RALASLAEVA GAAMTRRLPS ILNSLMDGII
ETKDEELKSE LENAFDTVLV SVDEFDGLNV AMNVMITLMK HDDHRRRAKA ALHLTKFFSE
ADLDYSRYHQ DLIRILLISF DDRDKEVVKA AWTALSGLTS HMRKEEMEVL AIPTRQILRQ
VGVAGADLPG FSLPKGIMAV LPIFLQGLLN GSVDQRTQSA LAMSDIIDRT GSASLKPFVT
QITGPLIRVV SERSVDIKCA IFYTLNKLLE KIPLAVKPFL PQLQRTFARG LADTSSETLR
NRAAKGLGIL ITLTPRVDPL IAELITGSKT SDLGVKNAMM KALQEVVGKA GGNMSETSRT
AILGLIDDDS SDQTDSVAIT NARLLGLLVK VLPAATAAPV IKNRVLSGQF SHASVLGLNA
LLAETPNTML EQFAEETPSV ICQGIANKDP FISDNSVLAA GKFLLADDGN HSFETNKAIF
EALAPVIQPG SPSDTRRLTL VVIRTVSRLH PELTRPHLAL LAPPIFASVR DLVIPVKLAA
EAAFLSIFSV VESDSDVFDK YMSGPGASLP PGPKRSMVEY FKRIGMRLAS QARERRNAEG
GEGGLGLSND EMDDEKELWS IGKVDLGDDT LGDE
//
