ID   A0A1V6T383_9EURO        Unreviewed;       592 AA.
AC   A0A1V6T383;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Homeobox domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PENFLA_c016G01690 {ECO:0000313|EMBL:OQE20722.1};
OS   Penicillium flavigenum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=254877 {ECO:0000313|EMBL:OQE20722.1, ECO:0000313|Proteomes:UP000191342};
RN   [1] {ECO:0000313|Proteomes:UP000191342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 14082 {ECO:0000313|Proteomes:UP000191342};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE20722.1}.
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DR   EMBL; MLQL01000016; OQE20722.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6T383; -.
DR   STRING; 254877.A0A1V6T383; -.
DR   OrthoDB; 450547at2759; -.
DR   Proteomes; UP000191342; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR   PANTHER; PTHR11850:SF212; TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG); 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000191342};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          209..272
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          414..437
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DNA_BIND        211..273
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          195..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          271..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..303
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   592 AA;  66413 MW;  DD28F8722756DCDE CRC64;
     MTPQPPFINP LTWQPSPQPL SDMEGMLDAN EPTGFMQEDP YLDTNTDYEF QPFLSDIGDL
     EWPQWTNYES HHVPTADTQP GHQEHEGLKA SEIVHDCSPA FAKENVGPSL SQPNLTNVSQ
     WLDGAYRPPV SCAHCRRHRL QCLILRTTPA NPNPRNACSS CVALFRECSL AKGEKRLPSV
     FETFSPVLGH LHGVPEDGNT LPATTVDNGD ERKEPKQFLR KGARVLREWF YQNQEYPYPT
     DAQKNQMAHE TGFSQKRIST WFANARRRQK QKIQSAGLSS TSRTRSGSPM VSSTLSSLTP
     MERWQASPPE DEPVPEAAIQ IAIASGSVES DDSIDPFQLD GSAMDFFNFD ESSSHLASSV
     SSIGSKASET SDSASSAWSY HSSADTGLPF PLLPKQTKPK RIRGRQRAAV DYHYQCTFCT
     QSFKKKHDWA RHEKSVHLTL DSWVCTPNLN DVQQAFELQF SECPFCDVLF PTSAHWEEHE
     FQVCADKPAQ ERTFSRKDYL WQHLRKFHSC TKVPVADLQA WRGSGVNVES RCGFCGCSLS
     TWSARAEHLA GHFKKGSRMD QWEGDWGLDA SALSVLRNAV PPSQRAIANM SI
//