ID A0A1V6T8R4_9EURO Unreviewed; 184 AA.
AC A0A1V6T8R4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 03-MAY-2023, entry version 20.
DE RecName: Full=60S ribosome subunit biogenesis protein NIP7 {ECO:0000256|PIRNR:PIRNR017190};
GN ORFNames=PENFLA_c012G02869 {ECO:0000313|EMBL:OQE22748.1};
OS Penicillium flavigenum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=254877 {ECO:0000313|EMBL:OQE22748.1, ECO:0000313|Proteomes:UP000191342};
RN [1] {ECO:0000313|Proteomes:UP000191342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 14082 {ECO:0000313|Proteomes:UP000191342};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- FUNCTION: Required for proper 27S pre-rRNA processing and 60S ribosome
CC subunit assembly. {ECO:0000256|PIRNR:PIRNR017190}.
CC -!- SUBUNIT: Interacts with pre-ribosome complex.
CC {ECO:0000256|PIRNR:PIRNR017190}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NIP7 family. {ECO:0000256|ARBA:ARBA00009895,
CC ECO:0000256|PIRNR:PIRNR017190}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE22748.1}.
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DR EMBL; MLQL01000012; OQE22748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6T8R4; -.
DR STRING; 254877.A0A1V6T8R4; -.
DR OrthoDB; 177185at2759; -.
DR Proteomes; UP000191342; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042255; P:ribosome assembly; IEA:InterPro.
DR CDD; cd21146; Nip7_N_euk; 1.
DR CDD; cd21151; PUA_Nip7-like; 1.
DR Gene3D; 3.10.450.220; -; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR040598; NIP7_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR016686; Ribosomal_synth_fac_NIP7.
DR InterPro; IPR005155; UPF0113_PUA.
DR Pfam; PF03657; UPF0113; 1.
DR Pfam; PF17833; UPF0113_N; 1.
DR PIRSF; PIRSF017190; Rbsml_synth_fac_NIP7; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88802; Pre-PUA domain; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017190};
KW Reference proteome {ECO:0000313|Proteomes:UP000191342};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017190};
KW RNA-binding {ECO:0000256|PIRNR:PIRNR017190}.
FT DOMAIN 97..172
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 184 AA; 20169 MW; 16CC816152B08B82 CRC64;
MRSLTEEETR TLFTKLASYT GRSLNSLITP AEDGSQSVFR LQGCRVYYVN KDIANLSVSF
PRDQLLSAGT MVGKFTKTGK FRINLTALDL LAQNARYKVW IKANGVMPLL YGGSVLKAHV
ARFSEDCPEN AGVVILDSND VPLGFGVTAR SSAQIAKLDP TSIAVHRQAD AGEYLREEDT
LFTT
//
