ID   A0A1V6TGE8_9EURO        Unreviewed;       244 AA.
AC   A0A1V6TGE8;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=HTH araC/xylS-type domain-containing protein {ECO:0000259|PROSITE:PS01124};
GN   ORFNames=PENFLA_c009G02999 {ECO:0000313|EMBL:OQE24980.1};
OS   Penicillium flavigenum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=254877 {ECO:0000313|EMBL:OQE24980.1, ECO:0000313|Proteomes:UP000191342};
RN   [1] {ECO:0000313|Proteomes:UP000191342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 14082 {ECO:0000313|Proteomes:UP000191342};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE24980.1}.
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DR   EMBL; MLQL01000009; OQE24980.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6TGE8; -.
DR   STRING; 254877.A0A1V6TGE8; -.
DR   OrthoDB; 1707513at2759; -.
DR   Proteomes; UP000191342; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.10.10; DNA Methylphosphotriester Repair Domain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR035451; Ada-like_dom_sf.
DR   InterPro; IPR004026; Ada_DNA_repair_Zn-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   Pfam; PF02805; Ada_Zn_binding; 1.
DR   Pfam; PF00165; HTH_AraC; 1.
DR   SUPFAM; SSF57884; Ada DNA repair protein, N-terminal domain (N-Ada 10); 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000191342};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT   DOMAIN          107..150
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000259|PROSITE:PS01124"
FT   REGION          154..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..171
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   244 AA;  26717 MW;  33D89D6DB917FE54 CRC64;
     MADIPKPQEI PRLSSNFTNA ERWQAIATRD VTANSFVYAV LTTKIYCRPS CPARLARRAN
     VQFYDTPLQA EKAGFRPCKR CRPHSGQTAA QSNPQTAMID KACESIRNIL TAGLKPKLRD
     LAMEAGLTPS HFHRVFKKRV GVTPGQYVES LVQSNLHSPE SSPSDAFSGF ETPRSASGDR
     GGEILDLDGN SEKGAGLSAA RSELPFMNGW NEFDALLASE SEQTWLPGLS IDPRMVLDVF
     DGTT
//