ID A0A1V6TM21_9EURO Unreviewed; 2888 AA.
AC A0A1V6TM21;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=FMP27 GFWDK domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENSTE_c004G05678 {ECO:0000313|EMBL:OQE27432.1};
OS Penicillium steckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=303698 {ECO:0000313|EMBL:OQE27432.1, ECO:0000313|Proteomes:UP000191285};
RN [1] {ECO:0000313|Proteomes:UP000191285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 24891 {ECO:0000313|Proteomes:UP000191285};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE27432.1}.
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DR EMBL; MLKD01000004; OQE27432.1; -; Genomic_DNA.
DR STRING; 303698.A0A1V6TM21; -.
DR OrthoDB; 607689at2759; -.
DR Proteomes; UP000191285; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019443; BLTP2/FMP27/Hobbit_C.
DR InterPro; IPR019441; FMP27/BLTP2/Hobbit_GFWDK_RBG.
DR InterPro; IPR019439; FMP27/BLTP2_N.
DR InterPro; IPR019409; FMP27_sixth_RBG.
DR InterPro; IPR019415; FMP27_SW_RBG.
DR InterPro; IPR019449; FMP27_WPPW_RBG.
DR InterPro; IPR045167; Hobbit.
DR PANTHER; PTHR15678; ANTIGEN MLAA-22-RELATED; 1.
DR PANTHER; PTHR15678:SF6; PROTEIN KIAA0100; 1.
DR Pfam; PF10293; DUF2405; 1.
DR Pfam; PF10351; FMP27-BLTP2_C; 1.
DR Pfam; PF10344; FMP27-BLTP2_N; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR Pfam; PF10305; Fmp27_SW; 1.
DR Pfam; PF10359; Fmp27_WPPW; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
DR SMART; SM01215; Fmp27_SW; 1.
DR SMART; SM01216; Fmp27_WPPW; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000191285};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1130..1232
FT /note="FMP27 SW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01215"
FT DOMAIN 1250..1409
FT /note="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01214"
FT DOMAIN 1655..2174
FT /note="FMP27 WPPW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01216"
FT REGION 95..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1894..1926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2001..2026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2043..2067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2504..2657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2741..2888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..736
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1906..1924
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2001..2022
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2045..2067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2548..2572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2754..2826
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2830..2846
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2851..2865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2888 AA; 326024 MW; 33885EA778CA3FB7 CRC64;
MTLFNPTSIL VGFLLLYLSS FFIFAIVRIA TGISIQRIGY FSLRRIAYAP REGLLIEIRG
LGFSLHPPSF AQPTWISIRL TDLKITVDTA TLARGKADST REQLGPASPK SPASPGSPKE
GTATPDSSTP RSKTWRTLTR VKERLKGLHK QINWLALVDV TAVNTAVHFL EAGQVQVGLL
SLTVDTRKKM VERGKLFRRK KDMSREQRPA EWILNVQNVL LAVDGREPIE VLDNVGVNLH
GLLYKDLEGL RDASVALKIG RLHIPYDDFN ILLKRIKSAQ KLAATKEPLP TETDDEISFA
DFVEELDKPG SRDDSIVQTV ADSKEFASSI LRGIQEIQVA LSFFRLSRGL QSLSGQNPVF
LNVVSHEIGV DLHRMDQKSP EHRMYFQRND VAHQALLAAI SLSVSLDDDS GETDNILYIP
MATTTIKTTL PSKTVSAFDE ENMEERNLNV LFANLVVTSP SLDLQPKHVS RLLKLAQARA
SSPRSKKRSN HHLISRLLPK ASIKLSVHEP VVRFVLPIEE SGAPGDYNLL ISSISSISLD
VESVHSAEGG AHYSLSSVYR IASHKFYYQT PAGNKHNLLT TENLELKTHL NASPQVCVIA
SGSINDCSVH MINGEVNRGI RQVLEQFRLH LQSQKRVPMP LNGRSVSPLR KVPPWLLSFS
FESTGLSLEV AGVDSPVSEI SRGVSLQLQS WTAEYKAQKT EHAVGSIARR RTSSQSTLGD
ESPFRFQPTS PPKNTQRGAA DGRRLAFHVR GFDGFVIESD DYLEPEPFFS LPRFEVALST
HSDRLGPVIH INSVFKGVYL QYSLYRFYCL GVAISVIQDV ISPLPSKEDS ASAQGKTRGA
PSISLPPPPS SPSPGKSELI TVDVKATIVQ LKANLPSNPA MMVQVYGLAG GSQRLSTPHV
KANLVRIHAE APKLKGVWAR IGSMNNVRLD FRKMRMKQGG KLTEERSIDL WADFIRIGVP
HHMVMHRIFD NLINTSKAFK QLHHRFKNRC KEFVSEREPE APKKVPRVSL RSKALLFELE
DDAFEWKLGC IYRTGLVEQV QRLAREEAFY LKTQKVRESD QKRASSRLRA KSSSRTLRSE
RTSQDTRRSR SAGPRSRKED KNHGGRGRKF RYDAEGATCI SSEYKIPAET AWERLQQHNA
QTWKEKIDAA LKFQGTSIKE VRNLFSGADE PPDDVKETET ILAIPNRPGL MSALISDVNL
VIDKPTFATE DIPSFLHKIG KGMPMDMKYG LLLPMNFNLE MGEARVNLRD YPLDLLHIPA
LRPGQSPRLP SWSLRTNFVV AEEFRNHESA RQVDVELVPK ADLSNGAHSD PFHIKVWRSV
TPVKTYSDPT IEINTSLPTS ISWGVSYQPV IQDMMKIIEG FTKPEVDPSE RVGFWDKIRL
SFHSRIKVLW KEDGDVHLRL KGSRDPYVVT GFGSGFVMCW RRDVKWEIHT SDDPMEFMSV
TSGEYVLAIP DYSAEARWAN ETTTEELESS SASSEQKNAA HFKKVVMKLS GDVKWAVGLV
FEREVDSDSR SFDFRPHYDV VLKNPKYVDS AERAGYDAFR GFRSDHIHLS VAVIAPQSRD
WSLDGIQPSS SYNTTHLSPR FFTHFFNWWS LFSGVMSLPV RQGPLFPGIT KTSKKFNRHL
ATVKYKLLLA PLFVAHIYKH KDNEEYAENV VTATGLKVRL DSLKLDVHQR REQIKMQARG
RSKQTKTSAM RMNHAIIDLQ SADFRAVSAS IEGTTAEDVA KNRDDIISTF QQPVPSVDLS
RFTIPDQNLD WIDMDDFVEP DWILPQESNP KTQILPLAFT PRFTYFRQTD HGDIGPEETG
YSTFGYEPTH DCVLSDTNDP RRVQIELTKD RLATVEAQIR NYDRTIGEQE LKLMKEVDHD
PELKEKHETY LRQAESLSRR RKFLTATLQR LERHLARDER TPKSGPNAPA SETSSRTGQY
AESTADGRAS GLDGLYSSAA DDFSSEFNNR FMIHNVQLKW NNSLRNIILR YSHQVSQRRG
FVYYMSRRAV KFILDIVEEQ NKNQRKNPKQ SKSHTRSDNE DENEVEDRIE ELLNSAKRYV
NAEDTEPSDS NNQSPSNSDD SSENLAPEFT PQNSYYLRLI APQIQLLSEK NRRSVLMIAA
KGMELKVVSI MDKERVSDDV SGLVQRRFSL EMDGAQFFVA TQKNLMANLQ FYAGNKYGNA
PGSAWPPWLT LEAMFDFELN PFGFSRIVQK TSATLRYDKY NNLRLKYNEE VAKGHPGPHP
GGDETRMDQI SVDFPHFRAI CDSAEYYTLY IIVLDLMMYS EPLEKVRNER LEKIMLMSDF
SDLRGTPEMV FKLQARIRQL EEIKEYFQIN AKYLDTQGWE DRLALERDLS QCEDELFFMM
EAITTSQRRA DPSASKTIHG ILRWSISASE VVWHLMKEAS APLVEFQLKN AQYERTDNTD
GSNHNLVAIE RVNGLNLLPD AIYPQIIAPY LDQPRPLDDY MLRVRWNMLE AVAGIPVVDN
FEVSLFPLKI QLERELGQRL FEYIFPNMGS GAFENGGFSP LMIKNMKPLD GSDDEDEEDD
NGEDLSRSVS TDGDSVFVDD LQTSKGPGSI ELRLQPTLSL SEESNSTKRQ GHLKGLAMTP
IHRNNTQLGV PEPRKLPRPA TTGALSKKKS ADSIRMLAKQ PTERSLSSHS TSAGEEKKKF
GMSKGSRRGK SSEPLDDLSQ MMSRASNYMT LAEVKVHDVV LCLSYKGKGE HNFEDLHNFV
FRLPVLEYSN KTWSNLDLAL RVKKDVIKAL ISHAPAILGN KFSQHRPTKQ QQKRFRELAS
SSQLLSSSHA LPPDHPSSMM SLDSNSEYSG SPSRKSMQSN ASPLARSISL NSETRGQEQD
NSLPDSRSAG DVDVDTRWEE SRRYINDPAR PMTSGQITTT IEANGSEQDD SHKKTIRAFG
RKLMGGRK
//
