ID A0A1V6TTP1_9EURO Unreviewed; 452 AA.
AC A0A1V6TTP1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=geranylgeranyl diphosphate synthase {ECO:0000256|ARBA:ARBA00012382};
DE EC=2.5.1.29 {ECO:0000256|ARBA:ARBA00012382};
GN ORFNames=PENSTE_c002G07547 {ECO:0000313|EMBL:OQE29758.1};
OS Penicillium steckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=303698 {ECO:0000313|EMBL:OQE29758.1, ECO:0000313|Proteomes:UP000191285};
RN [1] {ECO:0000313|Proteomes:UP000191285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 24891 {ECO:0000313|Proteomes:UP000191285};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- PATHWAY: Secondary metabolite biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005179}.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE29758.1}.
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DR EMBL; MLKD01000002; OQE29758.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6TTP1; -.
DR STRING; 303698.A0A1V6TTP1; -.
DR OrthoDB; 25272at2759; -.
DR Proteomes; UP000191285; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0046165; P:alcohol biosynthetic process; IEA:UniProt.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:0043386; P:mycotoxin biosynthetic process; IEA:UniProt.
DR GO; GO:1901663; P:quinone biosynthetic process; IEA:UniProt.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000191285};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004466}.
FT REGION 139..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 49352 MW; 541901F937B9724D CRC64;
MRARTVSAAG LIVTRTTSAP TSVCFQCLRH DSLPSPFPVQ SRKYHPTRRR DASPFGAAVS
AAQTIFKGMP KAPPGISVDP LRIVGKELKF LSKNIRQLLG SGHPALDKVA KYYTHSEGKH
MRPLLVLLMS QATAIDPRKL PAEQSNPSPV DNPLSQPSIL DDSNPDLNPL VSRATESHQY
NIAGDDNILA SQRRLAEITE LIHTASLLHD DVIDNAVTRR ASSSANTAFG NKMAVLAGDF
LLGRASVALA RLRDPEVTEL MATVIANLVE GEFMQLKNTA QDEAKPVYTD DTLNYYLQKT
YLKTASLISK SCRSSAVLGR CAPEVVEAAY SYGRNLGLAF QLVDDMLDYT VTEAEMGKPV
GADLELGLAT APLLFAWKSN PELGPLVGRK FREEGDVQKA RELVYQSNGV EQTRLLAQEY
ADKAVAAISD FPEGEAKSGL IEMCEKTMRR RK
//
