ID   A0A1V6TU23_9EURO        Unreviewed;       611 AA.
AC   A0A1V6TU23;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN   ORFNames=PENSTE_c002G02649 {ECO:0000313|EMBL:OQE29895.1};
OS   Penicillium steckii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=303698 {ECO:0000313|EMBL:OQE29895.1, ECO:0000313|Proteomes:UP000191285};
RN   [1] {ECO:0000313|Proteomes:UP000191285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 24891 {ECO:0000313|Proteomes:UP000191285};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE29895.1}.
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DR   EMBL; MLKD01000002; OQE29895.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6TU23; -.
DR   STRING; 303698.A0A1V6TU23; -.
DR   OrthoDB; 146204at2759; -.
DR   Proteomes; UP000191285; Unassembled WGS sequence.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR   CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR   Gene3D; 1.10.150.810; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR   InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR   InterPro; IPR022880; DNApol_IV.
DR   InterPro; IPR024728; PolY_HhH_motif.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR   PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR   Pfam; PF00817; IMS; 1.
DR   Pfam; PF11799; IMS_C; 1.
DR   Pfam; PF11798; IMS_HHH; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR   PROSITE; PS50173; UMUC; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000191285}.
FT   DOMAIN          104..283
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|PROSITE:PS50173"
FT   REGION          462..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          571..611
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        571..585
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..611
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   611 AA;  68714 MW;  1EF422F0BEDC80D1 CRC64;
     MAEDTTDGAV EDDTLKYQLL GPSLTKAGQD AVDQQKVSEI IYNASKGSKF FNHEQDRDRT
     QTLKIERLAA EKSRLEKLDL SHDLRRANEY LAELEMSRDL SQYVIHVDCD AFFAAVEELD
     RPELKTVPMA VGKGVLTTCN YVARKFGIRS GMASFVAKKL CPQLVLLPSN YEKYTAKATE
     IRGILAQYDP LFESASCDEA YLNITAYCDE NQMDPEEAVQ RLRAEVLENT KISVSAGIAP
     NAKIAKISSN INKPNGQFRV PNDRTAVLEF MRDLPVRKVN GIGRVFEREL DSIGIKTCGD
     IYPQRAMLTK LFGEKAFQFL AQCYLGLGRT NIEPVETHER KSVSTETTFH EIGDKEELRA
     KLRWAAEEME KDLTRTQFKG RTLCLKVKLH TFEVLTRQTA PPRAVSQAKD LYTYALPMLI
     KLEKEIPGMK LRLLGLRCSN LVSTQKTGLN FFGFTAQPKP MLGKPVDSDE PAGPAEPAEP
     VAETKEHDIE AEEAFEAAAL QEKQDEMNDL EQLSQEAMVS VPTTESESQP IAETSVQWEC
     PICSRPQPAH DREFNDHVDF CLSRQTIREA TQDTHSSTLD TPFSLTGGNR KRKPINAGGQ
     EDPRQKRLFF R
//