ID A0A1V6U284_9EURO Unreviewed; 1317 AA.
AC A0A1V6U284;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 13-SEP-2023, entry version 23.
DE RecName: Full=REM-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENSTE_c001G02502 {ECO:0000313|EMBL:OQE31963.1};
OS Penicillium steckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=303698 {ECO:0000313|EMBL:OQE31963.1, ECO:0000313|Proteomes:UP000191285};
RN [1] {ECO:0000313|Proteomes:UP000191285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 24891 {ECO:0000313|Proteomes:UP000191285};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE31963.1}.
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DR EMBL; MLKD01000001; OQE31963.1; -; Genomic_DNA.
DR STRING; 303698.A0A1V6U284; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000191285; Unassembled WGS sequence.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000191285}.
FT DOMAIN 122..191
FT /note="REM-1"
FT /evidence="ECO:0000259|SMART:SM00742"
FT DOMAIN 259..622
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 700..924
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 1107..1178
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1317 AA; 146504 MW; 9AC57AFE9AC4E298 CRC64;
MASGQQSAFS ASTQNRTLGD GRSSFSQDGA SDHAGSWGDA VPRSGRNGRS GSGGSGTTGT
RGPSSLAPSL APSLAPSLGG PGSFSSELKS MTSRSITPRA DGTYTRRASR SIGEEDLNTT
EERQAFLRDR IAKEIKIKTG TENMLEALLA KPPKQTKDQR LKVESELSTS NRKLIELQHE
LEEELLRAQA PSTTPPRSRL SSLFRGSPMR SPSRTHNDGG SVDGNPEADE DADMESPTYV
LSETLQALEM DAMSPDFYVE RANNLVELFK RHPTLKYDLA WPVFGLRVQI MLLSDSKEVV
AAGYRLTRYA IADRKSIQTI RALHTDELVI LSLVKESKSS IEREQALKFV RAFLDVKDGV
KEISRAVVRT IVSVAEHHED RLRNISIMTL AEMLVKDPEL VASSGGFSAL HDALAEGTFG
ASESLISSFL HILDTPRSRK YLQGSELEAV LTPFTDSLAD TLRNGRLKSA ARAISAMLKT
WPGIVILARN NAKPLHSLLE SLHYPDPQAR DLIMELLFDA LRIKPPSWSS SFLAGRRLTT
YGRVSNLRSD AESRHTRSFT ESTSNKFDLT AHFSTLILAA LIEAGLPKAL SDLIEDETDP
SLRRKATLLL TEVLKLAHHS LPSTASAKLQ VLPHLIPPAI RFDVDNHDVS TSTIFQIESI
NRTLARSGGY AGSGRYNMDV DYPASFLPGE PAKDKLSPAM DEQTFRNAIM ETHVLNTVNY
IKWKWDLIHR LVEGPLTNPK RMDEAIKGSK FMKRLIGFYR PFKYRFALVP NTKPNQRYVR
TGCALMRTLV QTPEGTKYLA ENKFLRQVAE CLAQLDRMSG LTSASPLFSR EQMANTLSGG
YFAMLGTLSG DAKGLLMMER WHMLNMCYHI IELQGRNDLI QTLLGNMDYG RDSHLRVMLS
KALTIGSKEI RIFATKLLRK YAVGGDTVST YVAISNAEWV VKLLVTQLYD PDVTVCQIAV
KILEEACNQR DYLEFVVKCR PSLDHLGEIG APLLLRFLST SVGYHYLDGL DYITQEMDDW
FLGRNDSYVA LVEAALSRAY VDQPRRSSYA PEDLVDMQDV GVVPPHFYRE LARTAEGCKL
LEQSGHFNEF ATTIQDFRLE EEDYEGLLKV KGCLWAVGNV GSMELGAPFL EPELVQQIVA
IAESAGVLTM RGTAFFVLGL ISRSTHGLRV LRDLGWDSAI DQNGEYLGYC LPAQYHKLFL
ISFPGYNAEA RRTSQDKLKE ATSDPDATNQ KILKLIVDMG NTVLSKRAAT DLHSMKSKQP
ERFHQVRLFR KTLCILESHH FRLPARRFAI DLFDKSVMRR IVLDEDSSSG TDSDSSS
//
