ID A0A1V6UHY1_9EURO Unreviewed; 517 AA.
AC A0A1V6UHY1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=3-hydroxyphenylacetate 6-hydroxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENCOP_c009G07535 {ECO:0000313|EMBL:OQE38056.1};
OS Penicillium coprophilum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=36646 {ECO:0000313|EMBL:OQE38056.1, ECO:0000313|Proteomes:UP000191500};
RN [1] {ECO:0000313|Proteomes:UP000191500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 31321 {ECO:0000313|Proteomes:UP000191500};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE38056.1}.
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DR EMBL; MDDG01000009; OQE38056.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6UHY1; -.
DR STRING; 36646.A0A1V6UHY1; -.
DR OrthoDB; 1584852at2759; -.
DR Proteomes; UP000191500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0043386; P:mycotoxin biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd11066; CYP_PhacA-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR46300:SF2; CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED; 1.
DR PANTHER; PTHR46300; P450, PUTATIVE (EUROFUNG)-RELATED-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000191500};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 517 AA; 57753 MW; 88E2EBFDEBABF577 CRC64;
MAIAAVLASL QGSVIQYPYH SIAAAALLVP ILYVILNEFV RDAARVKGMK GPRGLPLVGN
LAQIRTNAAE QYRLWSKKHG AVYQIQLGNI PVVVVNSAAS AKVLFSQNAQ ALSSRPETYT
FHKIVSNTAG TTIGTSPYSE SLKRRRKGAA SALNRPSVDT YVSHLDIESK AFVEELHRYG
NHGKTPVDPM PMIQRLSLSL ALTLNWGVRI ASQEEDLFDE ITEVEEEISR FRSTTGNLQD
YIPLLRLNPF SSNSKKAAEM RIRRDKYLGA LNRDLDDRMA KGTHKPCIQA NVILDKEAKL
NSEELTSISL TMLSGGLDTV TTLVAWSLGL LAQRPDIQDR AAKAIQEMYG EDEPMCSSED
DQKCAYIAAL VKECLRFFTV LRLALPRTSI KDITYKGITI PKGTVFFLNA WACNMDPDVW
TDPDEFRPER WLEQPDAPLF TYGMGYRMCA GSLLANRELY LVFIRTLNSF RLEPHDQTDC
HPLRGNSDPT SLVAIPQKYK VRFVPKNEKV LSKVLAQ
//
