ID A0A1V6UNP0_9EURO Unreviewed; 363 AA.
AC A0A1V6UNP0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=aristolochene synthase {ECO:0000256|ARBA:ARBA00039129};
DE EC=4.2.3.9 {ECO:0000256|ARBA:ARBA00039129};
GN ORFNames=PENCOP_c006G08038 {ECO:0000313|EMBL:OQE40042.1};
OS Penicillium coprophilum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=36646 {ECO:0000313|EMBL:OQE40042.1, ECO:0000313|Proteomes:UP000191500};
RN [1] {ECO:0000313|Proteomes:UP000191500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 31321 {ECO:0000313|Proteomes:UP000191500};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Sesquiterpene biosynthesis; aristolochene biosynthesis;
CC aristolochene from farnesyl diphosphate: step 1/1.
CC {ECO:0000256|ARBA:ARBA00037920}.
CC -!- SIMILARITY: Belongs to the terpene synthase family.
CC {ECO:0000256|ARBA:ARBA00006333}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE40042.1}.
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DR EMBL; MDDG01000006; OQE40042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6UNP0; -.
DR OrthoDB; 1828522at2759; -.
DR Proteomes; UP000191500; Unassembled WGS sequence.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR PANTHER; PTHR35201; TERPENE SYNTHASE; 1.
DR PANTHER; PTHR35201:SF4; TERPENE SYNTHASE; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000191500}.
SQ SEQUENCE 363 AA; 41325 MW; C63D268DA80824DE CRC64;
MLWIDGLCEY EKREENPKIQ RQIVPLKKNG GSLRLDIPHH GLVSIPLQED SSSGNIYPTG
SLKDVLIAHG SFRIAMQSWT QKKKEDPLEQ AVGEVKAISL FFPDVRSEHL RICMAAWLGV
LCTVDDLLEM MRPHEAENAI LETIATLQDN ERNNKKIYEV SPKATVCSLM SLFQNHCCQF
LSDAAAKDFF REICTVFCGF MQEIKFQQGY LKRDMQNYME IRTRTIGVAP FFSLIRCDLF
PPDYYPDSIL AIQKAVNVAV GLQNDLVGLE KDMDEQEPMN AVFVSMEELL RKEEMKGTKL
ADTIAAVCSL HNCSIAEVVQ MHQRILQAAG EESEIIVATS QLLFTETHLR WCTTAKRYRT
HLE
//
