ID A0A1V6UP08_9EURO Unreviewed; 646 AA.
AC A0A1V6UP08;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=UmuC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENCOP_c006G03433 {ECO:0000313|EMBL:OQE40141.1};
OS Penicillium coprophilum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=36646 {ECO:0000313|EMBL:OQE40141.1, ECO:0000313|Proteomes:UP000191500};
RN [1] {ECO:0000313|Proteomes:UP000191500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 31321 {ECO:0000313|Proteomes:UP000191500};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE40141.1}.
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DR EMBL; MDDG01000006; OQE40141.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6UP08; -.
DR STRING; 36646.A0A1V6UP08; -.
DR OrthoDB; 118267at2759; -.
DR Proteomes; UP000191500; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR041298; UBZ3.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45873; DNA POLYMERASE ETA; 1.
DR PANTHER; PTHR45873:SF1; DNA POLYMERASE ETA; 1.
DR Pfam; PF00817; IMS; 2.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR Pfam; PF18439; zf_UBZ; 1.
DR PIRSF; PIRSF036603; DPol_eta; 3.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
DR PROSITE; PS51907; ZF_UBZ3; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000191500};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 36..315
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT DOMAIN 566..600
FT /note="UBZ3-type"
FT /evidence="ECO:0000259|PROSITE:PS51907"
FT REGION 504..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 646 AA; 72424 MW; 499796D200009F71 CRC64;
MSEPTESSDP LKVSRFTYRQ LQGLRQGSTA TPLRVIAHID LDAFYAQCEM VRLGTTREVP
LAVRQWDSLI AINYAARPFG ISRLINVAEA KKLCPDLVLQ HVATFREGEG GRWAYRDDSF
RNISTDKVSL DPYRAQSRKI LQTMKEALAT WSADDTEVEP QNPKQELSAM LEKASIDEVF
IDLSPLIYRA LLQRYPELRM GTQDENRDAE LPIPPTTALQ WDTDCLVDLD QHQTEEDDPD
WDDVVMLIGS EIVRWVRNAV WEKLSYTCSA GLGRNKMIAK LGSACNKPNL QTVVRNRAVQ
NFLGGYKFTQ IRMLGGKLGD QITAAFGTEK VSELLNVPLE QMRTRLDDHT ASWLYGIIRG
DDRSEVNPRT QIKSMLSAKS FRPSINSLDQ AEKWLRIFAA DIYGRLVEDG VLENRRRPKV
ITMHHRTGTA QSRSRQTAIP GSNAINENLL YDLANTLLRQ VVADGQAWPC SNLSLSVSSF
EDGVTNNKAI EGFLVRGDQA KALNHSSRPR DADHLPSEQA PTEKRRKLDS DEGKIKSFFG
NPSHPDTTAG EPDCAQGPVE IDPELSAVPR FVCPRCSKSM LDYEKEEHDD WHFAKDLAIQ
DRDEAKVSHA PPPTKTARGT TARGRGSRGG GSRGKPEKGQ MRLAFH
//
