ID A0A1V6WUQ3_PENNA Unreviewed; 335 AA.
AC A0A1V6WUQ3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|PROSITE:PS50879};
GN ORFNames=PENNAL_c0186G05333 {ECO:0000313|EMBL:OQE66606.1};
OS Penicillium nalgiovense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60175 {ECO:0000313|EMBL:OQE66606.1, ECO:0000313|Proteomes:UP000191691};
RN [1] {ECO:0000313|Proteomes:UP000191691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|Proteomes:UP000191691};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE66606.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MOOB01000186; OQE66606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6WUQ3; -.
DR STRING; 60175.A0A1V6WUQ3; -.
DR OMA; MYIGALR; -.
DR OrthoDB; 2212647at2759; -.
DR Proteomes; UP000191691; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF25; RNASE H TYPE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000191691}.
FT DOMAIN 15..156
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 335 AA; 36969 MW; 398AC4013EE43589 CRC64;
MVMYIGALRA TPLYGPNPAV AYTDGSKTEN GGVGASAVTS RGNATARLND QDTVYAAELK
GILLALSQIK DDLVRELVAT SRAPARTMTI FTDNQAAIQA CAHPRRSSGQ QILRNIAIQI
ENLRLAAWRV RIHWIPGHMG VHGNERADIL AKLAASTYGP AEAVILLSGC RTKLRELAAE
RWKEEWASNN SGAYLRALFP EPTKAIFAIH ESLRRAASSV LVQMQTGKIG LPAYLAALPQ
WREQALENNP LRNPSRCTCD QGTMNTQHIL FSCPHFTELR HRILGLDRGG HDPWKEWLSK
PTLAVKAVNF LMQTKLLGQF RSLPTTYRVT NKVDS
//
