ID A0A1V6XFV9_PENNA Unreviewed; 520 AA.
AC A0A1V6XFV9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=RGS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENNAL_c0085G04061 {ECO:0000313|EMBL:OQE73956.1};
OS Penicillium nalgiovense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60175 {ECO:0000313|EMBL:OQE73956.1, ECO:0000313|Proteomes:UP000191691};
RN [1] {ECO:0000313|Proteomes:UP000191691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|Proteomes:UP000191691};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE73956.1}.
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DR EMBL; MOOB01000085; OQE73956.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6XFV9; -.
DR STRING; 60175.A0A1V6XFV9; -.
DR OMA; QFLWTRL; -.
DR OrthoDB; 1364107at2759; -.
DR Proteomes; UP000191691; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd08708; RGS_FLBA; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10845; REGULATOR OF G PROTEIN SIGNALING; 1.
DR PANTHER; PTHR10845:SF192; RGS DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000191691};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 232..300
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 334..476
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
SQ SEQUENCE 520 AA; 58831 MW; 98B9C321AB3A5ED0 CRC64;
MHQTASRLLR KTEDERPFTK DFMDLFSTSM VSLKLDSHRV RFTRYDHTFT SEEAINNLGS
LKFSQSNRMP DPKDPSRIVT TTTTTTFSMA KEMAQSVCQR FVDARFIESV DDKALSIFPL
KGSLFQLTPK GINILQRFCQ RNGITARHVM DVLESPRNTM QLVNLERDTE TDKLSHDCTT
IEIIFRRFAG QDGPNIKSSI STSDSDSLID YTSGIVGVKV AQERKLLDGK IYSNTFIGKA
SVDWLVNCST TVERRETCLI SELFLKYGLI TMIQDDKQIP NVGTNAHFQP SKYAIYGITE
RGQRVCGWIA REKTRELATT YGSRGMPRDT SNARLTHILQ DPALRLLFRE FLQYSLCEEN
LSFYLDVSEF TTNYHKAEKM GTFNEVDSVR GTLAAAYGLY NAFLAPGSPC ELNIDHTLRN
SLASRMTKAI EDDESMFNGL QEVVHLFELA QTSVFKLMSS DSVPKFLRDP KYSVILQEHD
VDIMGGPRSY SPTQAGPPSI PEHIMSRSAR AWQSPPQALI
//
