ID   A0A1V6XKD7_PENNA        Unreviewed;       646 AA.
AC   A0A1V6XKD7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=UspA domain-containing protein {ECO:0000259|Pfam:PF00582};
GN   ORFNames=PENNAL_c0071G01712 {ECO:0000313|EMBL:OQE75634.1},
GN   PNAL_LOCUS9524 {ECO:0000313|EMBL:CAG8286562.1};
OS   Penicillium nalgiovense.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=60175 {ECO:0000313|EMBL:OQE75634.1, ECO:0000313|Proteomes:UP000191691};
RN   [1] {ECO:0000313|EMBL:OQE75634.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 13039 {ECO:0000313|EMBL:OQE75634.1};
RA   Nielsen J.C., Nielsen J.;
RT   "Uncovering the secondary metabolism of Penicillium species provides
RT   insights into the evolution of 6-MSA pathways.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000191691}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 13039 {ECO:0000313|Proteomes:UP000191691};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
RN   [3] {ECO:0000313|EMBL:CAG8286562.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Branca A.L. A.;
RL   Submitted (JUL-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQE75634.1}.
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DR   EMBL; CAJVNV010000621; CAG8286562.1; -; Genomic_DNA.
DR   EMBL; MOOB01000071; OQE75634.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6XKD7; -.
DR   STRING; 60175.A0A1V6XKD7; -.
DR   OMA; CKNPRHL; -.
DR   OrthoDB; 1368087at2759; -.
DR   Proteomes; UP000191691; Unassembled WGS sequence.
DR   Proteomes; UP001153461; Unassembled WGS sequence.
DR   CDD; cd00293; USP_Like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR46100; IMP2'P; 1.
DR   PANTHER; PTHR46100:SF4; USP DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00582; Usp; 1.
DR   PRINTS; PR01438; UNVRSLSTRESS.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000191691}.
FT   DOMAIN          522..610
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
FT   REGION          36..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..227
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        247..271
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..339
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   646 AA;  70046 MW;  002560BDD72387A4 CRC64;
     MSYHTGRTSP IELKSLDGRS TISVTDKPSL SRALQTLHIS PSKSAGGTTY LPRAGGIRSP
     EPLISSPLRI SSSDMASAPS SPERHTADRE AFPRRSSDQV VDTVNSAAGR LTIDNDARPD
     VASTSLEQPH AKKRFLQARD RSQSRKGVAA IMSGRLFPRS FSRGRDRDSS RGSSQRGSSL
     DSRSASSPER GRPSSSDSHS VHVETLTPAP VTSGKGNSLN MQDTFNKSDE ALAKPHGSLP
     DYIKPTAVEE GGERLAKDVF DRDKNMIESS EDEANDTSSD EDSTLEGVRG RKKKKDSDIT
     SIMPSDFEKS KEDNSKQAEE QKVPDLPSGR QEKKPRKSAL KAVVHPQTSF DIPTPRVHSV
     AGTPYGSEDE AEIGDIHRAQ KLSISMSAID NGVHNRSIRT IVRGNFSSPQ DQGDGIRRRR
     RKYLIATDLS EESVYALEWT IGTVLRDGDT IFAIYAMHED STTASGVQVG EGAKVMKDTT
     AVVGTQTKEA NQNYGSRTIL GRLGPGTASK THSADSRASS IAEAERVRAV ETVSQTCVKL
     LRKTVLQVRI AVEVIHCKNP KSMITEAIDE LEPTLVIVGA RGQSALKGVL LGSFSNYLLS
     SSSVPVMVAR RKLKRHTWKD KLKGTANVRL SNNLVTPKSL AQAKVD
//