ID A0A1V6YFJ4_PENNA Unreviewed; 307 AA.
AC A0A1V6YFJ4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Ribose-5-phosphate isomerase {ECO:0000256|ARBA:ARBA00019150};
DE EC=5.3.1.6 {ECO:0000256|ARBA:ARBA00011959};
DE AltName: Full=D-ribose-5-phosphate ketol-isomerase {ECO:0000256|ARBA:ARBA00032273};
DE AltName: Full=Phosphoriboisomerase {ECO:0000256|ARBA:ARBA00029734};
GN ORFNames=PENNAL_c0022G10279 {ECO:0000313|EMBL:OQE86048.1},
GN PNAL_LOCUS2953 {ECO:0000313|EMBL:CAG8039055.1};
OS Penicillium nalgiovense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60175 {ECO:0000313|EMBL:OQE86048.1, ECO:0000313|Proteomes:UP000191691};
RN [1] {ECO:0000313|EMBL:OQE86048.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|EMBL:OQE86048.1};
RA Nielsen J.C., Nielsen J.;
RT "Uncovering the secondary metabolism of Penicillium species provides
RT insights into the evolution of 6-MSA pathways.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000191691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|Proteomes:UP000191691};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
RN [3] {ECO:0000313|EMBL:CAG8039055.1}
RP NUCLEOTIDE SEQUENCE.
RA Branca A.L. A.;
RL Submitted (JUL-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate;
CC Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273;
CC EC=5.3.1.6; Evidence={ECO:0000256|ARBA:ARBA00001713};
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribose
CC 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step
CC 1/1. {ECO:0000256|ARBA:ARBA00004988}.
CC -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
CC {ECO:0000256|ARBA:ARBA00008088}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE86048.1}.
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DR EMBL; CAJVNV010000099; CAG8039055.1; -; Genomic_DNA.
DR EMBL; MOOB01000022; OQE86048.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6YFJ4; -.
DR STRING; 60175.A0A1V6YFJ4; -.
DR OMA; ACHVQEK; -.
DR OrthoDB; 5232260at2759; -.
DR UniPathway; UPA00115; UER00412.
DR Proteomes; UP000191691; Unassembled WGS sequence.
DR Proteomes; UP001153461; Unassembled WGS sequence.
DR GO; GO:0004751; F:ribose-5-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:InterPro.
DR CDD; cd01398; RPI_A; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1360; -; 1.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR004788; Ribose5P_isomerase_type_A.
DR NCBIfam; TIGR00021; rpiA; 1.
DR PANTHER; PTHR11934; RIBOSE-5-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11934:SF0; RIBOSE-5-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF06026; Rib_5-P_isom_A; 1.
DR SUPFAM; SSF75445; D-ribose-5-phosphate isomerase (RpiA), lid domain; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000191691}.
SQ SEQUENCE 307 AA; 32976 MW; 8D7E4335C7F3E6A4 CRC64;
MIQSTLISPL FLCRRLTPTI PTLFRTLQSP QRRQFTMSAV EEAKRAAAKV AVEKHYPKDA
RWVGIGSGST IVYVVEAITN LGVDTSNTKY IPTGYQSKQL IVNAGLMAVE YDALPLGTVL
DVAFDGADEV DEDLNCIKGG GACLFQEKIV ALQAKEFICV ADHRKLQPRL LTSWKSIPIE
VAPIAAYRVV QKLKELGSVN PAVRPSASVK EGPLKTDQGF FIVDAPFKPM LIKADIEAGQ
DGNGKDGVWA VEVLARKIKE IIGVLEVGIF HGQTGPQAAA AGGLGGQRPV AAYFGMSDGT
VAVRKAE
//
