ID A0A1V6Z3R9_PENNA Unreviewed; 291 AA.
AC A0A1V6Z3R9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=HORMA domain-containing protein {ECO:0000259|PROSITE:PS50815};
GN ORFNames=PENNAL_c0004G06949 {ECO:0000313|EMBL:OQE94287.1},
GN PNAL_LOCUS472 {ECO:0000313|EMBL:CAG7950228.1};
OS Penicillium nalgiovense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60175 {ECO:0000313|EMBL:OQE94287.1, ECO:0000313|Proteomes:UP000191691};
RN [1] {ECO:0000313|EMBL:OQE94287.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|EMBL:OQE94287.1};
RA Nielsen J.C., Nielsen J.;
RT "Uncovering the secondary metabolism of Penicillium species provides
RT insights into the evolution of 6-MSA pathways.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000191691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|Proteomes:UP000191691};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
RN [3] {ECO:0000313|EMBL:CAG7950228.1}
RP NUCLEOTIDE SEQUENCE.
RA Branca A.L. A.;
RL Submitted (JUL-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE94287.1}.
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DR EMBL; CAJVNV010000011; CAG7950228.1; -; Genomic_DNA.
DR EMBL; MOOB01000004; OQE94287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6Z3R9; -.
DR STRING; 60175.A0A1V6Z3R9; -.
DR OMA; KEEQTWI; -.
DR OrthoDB; 448945at2759; -.
DR Proteomes; UP000191691; Unassembled WGS sequence.
DR Proteomes; UP001153461; Unassembled WGS sequence.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF10; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Reference proteome {ECO:0000313|Proteomes:UP000191691}.
FT DOMAIN 33..240
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 291 AA; 31805 MW; F8F0C3A816E4B029 CRC64;
MPIASESSST TTTTMTTFSA PVPATKSLPT NQSALAASFT NFLTVSVHQI LFLRSVYPRA
TFLPVRAYNY PVRQSRHPKV CDYINDASIA VGTEILKGTI TAVSIIISSL RTNQPLERYA
FDLSGFPRAP AGEMNTTFED RNEDSSNPGA PVSDRGPAPT SVDLEAQFRA CLARLASACA
RLTPLPRDDE FSFTVCIEVR EDALPPAGTT KEEQTWIVAE PGKVHLRSCT APFSVSKLRN
GEPQQAPPKV SNGRAKTVPV RRVEAGELRL ELWVEEARQK FNEPVDSEQP P
//
