ID   A0A1V8SC12_9PEZI        Unreviewed;      1275 AA.
AC   A0A1V8SC12;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   28-JUN-2023, entry version 22.
DE   RecName: Full=MIF4G domain-containing protein {ECO:0000259|SMART:SM00543};
GN   ORFNames=B0A48_17516 {ECO:0000313|EMBL:OQN96460.1};
OS   Rachicladosporium antarcticum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Cladosporiales; Cladosporiaceae; Rachicladosporium.
OX   NCBI_TaxID=1507870 {ECO:0000313|EMBL:OQN96460.1, ECO:0000313|Proteomes:UP000192596};
RN   [1] {ECO:0000313|Proteomes:UP000192596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCFEE 5527 {ECO:0000313|Proteomes:UP000192596};
RA   Coleine C., Masonjones S., Stajich J.E.;
RT   "Genomes of endolithic fungi from Antarctica.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQN96460.1}.
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DR   EMBL; NAJO01000066; OQN96460.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V8SC12; -.
DR   STRING; 1507870.A0A1V8SC12; -.
DR   InParanoid; A0A1V8SC12; -.
DR   OrthoDB; 276824at2759; -.
DR   Proteomes; UP000192596; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   Gene3D; 4.10.80.160; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 2.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 2.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192596}.
FT   DOMAIN          473..663
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          678..885
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          243..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          913..985
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1142..1247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        426..456
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        915..946
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        963..985
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1167..1190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1209..1223
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1275 AA;  143299 MW;  A0973B0B4B9D09C6 CRC64;
     MERQRKRDLK ELNTRAWDGE QGVFPVQGSL DSNLKKNTAF IKRVRTAITI ASLPTFLLEV
     RTLSLHKYLT EIVSACYEGL CRLKTPGEVA AGVEVVSALH QRFGPEEFTC NLGWLIGRGL
     STPDRAQLKA LSAEVRDREE KDRIARQRVL LRVATELWLV SALRSLEDVT KPDETGRGTK
     GAELMPKAKT NGLKIGATDA EPFPLEVLKD MLSHDREHVN LPLVVLFVKS FAWDVLGSAG
     TKKDARQAVA DNGETTAEPK INGHTETPAS TDDDEVVIQD TPLTTSHVQQ RFRNILERYF
     EDVKTHILRD QKNLTSQSKR NAEAYVKSGE VFEDRQTNYE KAVKAQERLI ASTQTLADAL
     GAEMPDLSEK EAAGSAFDSG IGLVKTGEYL RGQSEGAGIW EDEDERRFYE NLVDLKDRVP
     SILLEEPRRK NADGDEQVGK RSDETADARP DSRDAAADDT STAIANKTVG AQVDAVLARL
     HELATKDQVD QLAYDFCFLN SKASRNRLIK AIEEIPKGRT DLLPLYGRLI ATLGRYLTDV
     PQAITKHLDE EFRSLQRRKS KDFLGQVRLV NVRYIAELTK FDVAQEHFIF HCLKVSLEDF
     SRMNIEIIAM LLENCGRYLL RNPKTSPRMT SFLDTLQRKK AAQHLGQHER MLIENAMYYA
     DPPARAAIQQ KERTSLDTYI RKLAYLDLNK KSLEKVIKQI RKLHWEEDEV VEYLRKIFIK
     PGKIKYSNLY LLAVMLGALH RHHTDFAVSV LDELLERIVV GLEINDFRYR QRQTAEAKYL
     GELYIYRMVD STLIFDTLYK LLNYGHDGYP QPGKICPIDL PDDYFRINLV CALLDTCGMY
     FEKGAARKKL DFFLSFLQYY VNTKDPAPME VDYMLQETYG LLRPHWKPVL NDFNAAASAF
     AEACKLNYQD TAASKTVDPE DDADLNATGD VRPGHDDSRD IEDKSGEDDT AEPVDSPQQN
     EGLDSDDEEH IVVTRPEEQR DPEAEADFDR ELAKLMAESV ESRKFDRKPV FDVALPMRKS
     AREVSAPVAT AEDSGGDSRP HTPVYEAGKM KFALLSKKGN RQQTRSIDLP SDSTFAIELR
     KQQEAERAEQ QRIKNLVLNY DLMDDQADGD SPSFHYVNNS NSKRTQFVGK GALNKRLSSN
     TAYVKPGSGR IQQATTKARD PVPGCSSPLQ ADTSTATLLL PPSELTTDPQ ADNPEAVFES
     PHIQPRADKS GNTRSKQRAR KLQLGDLDWY GNTRPSASIP AATAREKGDV SLDAFVVDKG
     QNKAKKGIGQ GANKG
//