ID A0A1V8TCV2_9PEZI Unreviewed; 684 AA.
AC A0A1V8TCV2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Serine/threonine-protein kinase fhkC {ECO:0008006|Google:ProtNLM};
GN ORFNames=B0A48_05979 {ECO:0000313|EMBL:OQO09088.1};
OS Rachicladosporium antarcticum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Cladosporiales; Cladosporiaceae; Rachicladosporium.
OX NCBI_TaxID=1507870 {ECO:0000313|EMBL:OQO09088.1, ECO:0000313|Proteomes:UP000192596};
RN [1] {ECO:0000313|Proteomes:UP000192596}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCFEE 5527 {ECO:0000313|Proteomes:UP000192596};
RA Coleine C., Masonjones S., Stajich J.E.;
RT "Genomes of endolithic fungi from Antarctica.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC protein kinase family. CHEK2 subfamily.
CC {ECO:0000256|ARBA:ARBA00005575}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQO09088.1}.
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DR EMBL; NAJO01000011; OQO09088.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V8TCV2; -.
DR STRING; 1507870.A0A1V8TCV2; -.
DR InParanoid; A0A1V8TCV2; -.
DR OrthoDB; 20430at2759; -.
DR Proteomes; UP000192596; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd05117; STKc_CAMK; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR44167:SF22; DNA DAMAGE RESPONSE PROTEIN KINASE DUN1; 1.
DR PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000192596}.
FT DOMAIN 190..242
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 281..546
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..647
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 311
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 684 AA; 76480 MW; D291729EB471B31C CRC64;
MAPNAEKSAL KRARVSIDEA LDTKKPRRSA RLSNAPDRED GEEQLKNNGA LPSPVTKAST
DTTEGARAFT PTPDFIEQRA TPEASPSHGS HRPGLSSPPS DTQPFSQFLP PPPYSYEVED
EAAEGVWGYL VPIDGVSETL VLRKRAACQV PSKGLTDPHG KKKVPKKHYK EAEEKYEGQK
AEKGVPAGGY LIGRHPECDR LVQSPTVSNR HCLLFCENKN GDSLAVVEDL SGNGTYVNDA
FIGRNKRREL ADGDELSILD EARFIFRYPR NRDTNAFRSQ YTIQGQLGKG HFATVYLATE
KQSGLRYAVK KFEKRSGPGE RSKVEGLQQE IAVLMAISHP NMLCLKDTFD ESDGVYLVLE
LAPEGELFNW IVTKQKMTES ETRKIFAQLF QGVKYMHERN IVHRDIKPEN ILLIDKELHV
KLADFGLAKI IGEESFTSTL CGTPSYVAPE ILEQSNRRRY TRAVDVWSLG VVLYICLCGF
PPFSDELYSA ENPYTLSQQI KMGRFDYPSP YWDAVGDPAL DLIDRMLTVD SDKRITIDEC
LEHPWLTQQP MTLTDSTDGL TGALAGLDFT RRKPVRERTL LSSINDVRVG KVLNSQKPDQ
PAVKVWDKNQ GTKKLAPQQR SKAKGGHFEQ TLEQEVAIEE RPDAARDPQE FMGMGGKGDE
QLFEEQTGSI YPGETIKEVK GEEK
//
