ID A0A1V8TJA5_9PEZI Unreviewed; 1051 AA.
AC A0A1V8TJA5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=B0A48_03186 {ECO:0000313|EMBL:OQO11459.1};
OS Rachicladosporium antarcticum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Cladosporiales; Cladosporiaceae; Rachicladosporium.
OX NCBI_TaxID=1507870 {ECO:0000313|EMBL:OQO11459.1, ECO:0000313|Proteomes:UP000192596};
RN [1] {ECO:0000313|Proteomes:UP000192596}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCFEE 5527 {ECO:0000313|Proteomes:UP000192596};
RA Coleine C., Masonjones S., Stajich J.E.;
RT "Genomes of endolithic fungi from Antarctica.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQO11459.1}.
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DR EMBL; NAJO01000006; OQO11459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V8TJA5; -.
DR STRING; 1507870.A0A1V8TJA5; -.
DR InParanoid; A0A1V8TJA5; -.
DR OrthoDB; 5476523at2759; -.
DR Proteomes; UP000192596; Unassembled WGS sequence.
DR GO; GO:0031261; C:DNA replication preinitiation complex; IEA:UniProt.
DR GO; GO:0042555; C:MCM complex; IEA:InterPro.
DR GO; GO:0005656; C:nuclear pre-replicative complex; IEA:UniProt.
DR GO; GO:0043596; C:nuclear replication fork; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR GO; GO:0006279; P:premeiotic DNA replication; IEA:UniProt.
DR CDD; cd17755; MCM4; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR008047; MCM_4.
DR InterPro; IPR018525; MCM_CS.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF66; DNA REPLICATION LICENSING FACTOR MCM4; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF21128; MCM4_WHD; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR PRINTS; PR01660; MCMPROTEIN4.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00847; MCM_1; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000192596}.
FT DOMAIN 630..838
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
FT REGION 1..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 891..918
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 114866 MW; 0BA1B40E4A82B1CE CRC64;
MSSPAQRRSN RNSVNGTPRR SSQRSSQAPA SSPALPTNTN GNDEHRSDAA RSDTTPRGQA
RYSQNLSQSQ APPTSSPLFF GSSPNGGESQ SQSQSQSRLG VPQGNGATNA SSSLRRQVAN
GSSEGGRTPR AHAGYGDSSP IHYVSSSDPA GPTTNGHRAP HTSSSGLFVR SSAGNAPQSA
RERRHDLDSA LLENGTGPRR RLLVDANGMP VPADSDAATF SNLNPNTSDA NALGGDSMNV
IWGTNVSLVD SFNAFKDFLF NFERKYRLSA EGEVPDGETL DAGHPAREKE YVKMMETMLD
LGVRFMYLDC KNLKAYPPTR KLWHQLQSFP SEIIPLIDSA IKDCIIDLAE KRMEQMRATQ
SQQRVNAANG TRDSSAPPMP SSDIDNDMGG RTPRAEANVQ EEIPDLVAEI EARIFRVRPL
GLDKTINLRD LNPGDMDKMI SIKGLVIRTT PVIPDMKDAF FRCSVCHHSV KVEIDRGKIA
EPTRCPREVC SQSNSMQIVH NRSGFADKQV IKLQETPDSV PDGQTPHSVS ICAYDELVDM
CKAGDRVEVT GIFKCNQVRI NPRQRSVKNV FKTYVDCLHI QKVDKRRMGI DPTTIEEELS
EQVSGSIEET RKVSEEEEAR IQGVASRHDV YELLSRSLAP SIYEMEDVKK GILLQLFGGT
NKSFEKGGSP KYRGDINVLL CGDPSTSKSK MLEYIHKIAP RGVYTSGKGS SAVGLTAYIT
RDPETRSLVL ESGALVLSDG GVCCIDEFDK MSDSTRSVLH EVMEQQTVSI AKAGIITTLN
ARTSILASAN PIGSKYNPNL PVPQNIDLPP TLLSRFDLVY LVLDRIDETA DRKLARHLVG
MYLEDTPDHA TRDEVLPVEF LTSYISYARA NIHPTITPAA GEALVKAYVA MRKLGEDIRA
AERRITATTR QLESMIRLAE AHAKMRLSET VTEADVAEAV RLIQSALKQA ATDARTGLID
MGLLTEGTSA SERRRKEDLK HGVLEVLDDM LRAGGSTVRY GDVVRTLSEQ SSVPVEGAEF
AEAVRALEQE GKVQMLGEGA RRSIRRVTGG M
//
