ID   A0A1V8TKC8_9PEZI        Unreviewed;       686 AA.
AC   A0A1V8TKC8;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=O-acyltransferase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=B0A48_03399 {ECO:0000313|EMBL:OQO11672.1};
OS   Rachicladosporium antarcticum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Cladosporiales; Cladosporiaceae; Rachicladosporium.
OX   NCBI_TaxID=1507870 {ECO:0000313|EMBL:OQO11672.1, ECO:0000313|Proteomes:UP000192596};
RN   [1] {ECO:0000313|Proteomes:UP000192596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCFEE 5527 {ECO:0000313|Proteomes:UP000192596};
RA   Coleine C., Masonjones S., Stajich J.E.;
RT   "Genomes of endolithic fungi from Antarctica.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sterol O-acyltransferase that catalyzes the formation of
CC       stery esters. {ECO:0000256|ARBA:ARBA00023568}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the membrane-bound acyltransferase family.
CC       Sterol o-acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00009010}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQO11672.1}.
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DR   EMBL; NAJO01000006; OQO11672.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V8TKC8; -.
DR   STRING; 1507870.A0A1V8TKC8; -.
DR   InParanoid; A0A1V8TKC8; -.
DR   OrthoDB; 9612at2759; -.
DR   Proteomes; UP000192596; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   InterPro; IPR004299; MBOAT_fam.
DR   InterPro; IPR014371; Oat_ACAT_DAG_ARE.
DR   PANTHER; PTHR10408; STEROL O-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR10408:SF9; STEROL O-ACYLTRANSFERASE 1-RELATED; 1.
DR   Pfam; PF03062; MBOAT; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192596};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        266..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        291..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        611..631
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        666..685
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          360..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  78176 MW;  6063A17A261A3661 CRC64;
     MHSDQTSGIA QVTGSLGQDG IAVLDSGRQD LTEDGVRSHD FASRSRSESA LHDEVDSDDS
     VEDYDDIRLD PDTLVANTMP SVDDSLRPAG KTGMKDDYRR RQSEPGLDLK SARKGIQIKL
     EKTDRKGRYV LTADDPEIRE ILRKGLEREE REAAGKRPRT RIRDLVFTRQ FTTFDRQNPT
     SAESPFFGFF TLFWLAMVLI FVQTALNNWR AYGSILGDNQ IAKLMFSREL LTLGITDGVI
     CAATSEAYFL QLAISKGWIN WAKSGWIIQN LWQTAYLGTI LWWTWFRDWP WTHSVFIVLH
     ALVFVMKQHS YAFYNGYLSG VYRRRALLER KLKQLDAIEP VSSPPSSPLG MPTFGARSAS
     VDLGKPNEET DSTLKPRRPF VGNRTSTNLA IEKSDVASVA SAIESGKPLD LDQLQAFRHV
     IQEEIAELST QLSGKSQSPT SANVYPHNLR LGNFAEFICL PTLVYELEYP RQERINWWYV
     AEKTTATFGV LCVMQVISQA FIYPPVAKTV AMKEAGLTMA ERWVEFPFIV SDMLFALLLE
     QLLTWYVIWE CILNVLAEVT RFADRGFYGD WWNSVSWDQY ARDWNRPVHN FLLRHVYHSS
     ISTFHLSRHS ATFVTFLLSA LVHELVMAVM FKKVRGYLFA MQLLQMPLVS LSRTKLLKGR
     TILGNVIFWL GLFVGPSFLT SLYLIL
//