ID A0A1V8TR44_9PEZI Unreviewed; 1264 AA.
AC A0A1V8TR44;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=RhoGAP-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B0A51_15167 {ECO:0000313|EMBL:OQO17202.1}, B0A51_17292
GN {ECO:0000313|EMBL:OQO13830.1};
OS Rachicladosporium sp. CCFEE 5018.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Cladosporiales; Cladosporiaceae; Rachicladosporium.
OX NCBI_TaxID=1974281 {ECO:0000313|EMBL:OQO13830.1, ECO:0000313|Proteomes:UP000192386};
RN [1] {ECO:0000313|EMBL:OQO13830.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCFEE 5018 {ECO:0000313|EMBL:OQO13830.1};
RX PubMed=28684563;
RA Coleine C., Masonjones S., Selbmann L., Zucconi L., Onofri S., Pacelli C.,
RA Stajich J.E.;
RT "Draft Genome Sequences of the Antarctic Endolithic Fungi Rachicladosporium
RT antarcticum CCFEE 5527 and Rachicladosporium sp. CCFEE 5018.";
RL Genome Announc. 5:e00397-17(2017).
RN [2] {ECO:0000313|Proteomes:UP000192386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCFEE 5018 {ECO:0000313|Proteomes:UP000192386};
RA Coleine C., Masonjones S., Stajich J.E.;
RT "Genomes of endolithic fungi from Antarctica.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQO13830.1}.
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DR EMBL; NAEU01001480; OQO13830.1; -; Genomic_DNA.
DR EMBL; NAEU01001067; OQO17202.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V8TR44; -.
DR STRING; 1974281.A0A1V8TR44; -.
DR Proteomes; UP000192386; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09394; LIM1_Rga; 1.
DR CDD; cd09395; LIM2_Rga; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00132; LIM; 2.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000192386};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 27..89
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 1070..1260
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 823..885
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 189..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..469
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..604
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1264 AA; 136976 MW; 2B46D7F5B42E2393 CRC64;
MTTIAPAMES PTNFPESPLE GEGEDVYPCK GCGEILEEGK AFELAGNRWH IDCFRCNTCG
TLLDSDANLL LLGDGSLICN NCTYSCNACG NKIEDLAILT GDQAFCASCF RCRNCKRKIE
NLRYARTSQG IFCMSCHESL MARRRKKSKG TPRPSAPSAT RSGSAIEKAL PSLPPGAAPE
AAFSPDSETP PMETYTAGTN ANSPPPRALR PTKDGAADKF KRDVSPMSDE ARRDGQTLPA
STYKESRSSH ISSGSDDGEN EGFLPMAFDP APAPRPPQIA RKKLPQSSDL SQQIALDSPP
PRDYFAGRSA SKPHRDALRE DRSVSSRSAS TERDPSHAAT LGSTKPSPHI AYQDKSRAHK
KVTSNSGQST PGALSTAQHS PSFAGATDRT ERPKAQTLNT GSYTLGPGEG FKLQEVPKEK
RAASRSSSSK ENRSPVIVSP VDAAEKGNDR LEPTVTASPV STDSPQSGVN PFDDPRRREG
PPSAAPPAPP KFQERPTRGD SLATGQLKPS ASVRSTPPTP TTSLAPNAQL SAHSRDTSSV
SIPASFTDAQ STISAKTVES PTNRSSFDVP PRASSRPMGA PKPATNNDFV TPRLPPPPPP
PAELHRTQES ISTRPSTDSR SDAQRSPALL SAGLQRQSTD GGFNMEEEMA RILRGEKANR
DSHPEATQSV LRRVSKAVKH GRSFSDRGAT ATKSPSVTAG EVPGTPMTIS SPIMTSPAAK
ESVDSLRASL RRAQQKITQL ETEKQVLEEK VNSSSDIRQV NSELKEKRST MAFLDTQREM
VVRELEVMTN HLGKAKDSNQ PLDMPTLKDS VLQELSESLN KLKDHMGSQI EDLIRRRNEL
TDEITNLIQM KDKGFQEYDI LSTKNEQLER MNNQLTQNFQ EFYKSNRGAN GGAPDVWKSG
ATNGLGIYHP GAKPDSQLTS EMRSLNLVST DSSLPNLLHE TEAEPATILT APQMVNIRKG
QPKKFNWRKG GAKAVTNVTK GLKGAFANND RVTTRDGLDI GVPYSSTQQT VAGSEQSSIN
SKQGLQPNGL GWLAQKNGGL KAGSLGSTMR NGSSTNLTIA AGDGSVLFGT ELELRCDYEK
RVIPIIVTRC IEEVEARGMD VEGVYRKSGG SGQVKNVQAG FEKEGTFDVS DEDLDIHAVT
STLKQYFRKL PTPLITYDVY DTLLEAGQTS TVGDREQQML ALRAAVHELP EAHRNCLEIL
ICHLARVMTR QEKNLMTPLN LAVVFAPTIM RPLSIEREMN DMLLQRTAVQ AMIELCDGVF
GEEE
//
