ID   A0A1V8V3H6_9PEZI        Unreviewed;       905 AA.
AC   A0A1V8V3H6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Poly A polymerase head domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=B0A51_02801 {ECO:0000313|EMBL:OQO30459.1};
OS   Rachicladosporium sp. CCFEE 5018.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Cladosporiales; Cladosporiaceae; Rachicladosporium.
OX   NCBI_TaxID=1974281 {ECO:0000313|EMBL:OQO30459.1, ECO:0000313|Proteomes:UP000192386};
RN   [1] {ECO:0000313|Proteomes:UP000192386}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCFEE 5018 {ECO:0000313|Proteomes:UP000192386};
RA   Coleine C., Masonjones S., Stajich J.E.;
RT   "Genomes of endolithic fungi from Antarctica.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TTI2 family.
CC       {ECO:0000256|ARBA:ARBA00034736}.
CC   -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC       polymerase family. {ECO:0000256|ARBA:ARBA00007265,
CC       ECO:0000256|RuleBase:RU003953}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQO30459.1}.
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DR   EMBL; NAEU01000050; OQO30459.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V8V3H6; -.
DR   STRING; 1974281.A0A1V8V3H6; -.
DR   Proteomes; UP000192386; Unassembled WGS sequence.
DR   GO; GO:0110078; C:TTT Hsp90 cochaperone complex; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001680; P:tRNA 3'-terminal CCA addition; IEA:UniProt.
DR   CDD; cd05398; NT_ClassII-CCAase; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR002646; PolA_pol_head_dom.
DR   InterPro; IPR032828; PolyA_RNA-bd.
DR   InterPro; IPR018870; Tti2.
DR   PANTHER; PTHR13734:SF5; CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13734; TRNA-NUCLEOTIDYLTRANSFERASE; 1.
DR   Pfam; PF01743; PolyA_pol; 1.
DR   Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR   Pfam; PF10521; Tti2; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE   3: Inferred from homology;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192386};
KW   RNA-binding {ECO:0000256|RuleBase:RU003953};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT   DOMAIN          65..229
FT                   /note="Poly A polymerase head"
FT                   /evidence="ECO:0000259|Pfam:PF01743"
FT   DOMAIN          256..318
FT                   /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT                   and SrmB- binding"
FT                   /evidence="ECO:0000259|Pfam:PF12627"
FT   REGION          376..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          580..604
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..395
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   905 AA;  101543 MW;  0A1CAA578A84C9AE CRC64;
     MAPMIQEFED VPSPGTKIEL TDVESSLRRL LLDVAAYIDK DPPASYDEYG NCVIPKHLQD
     QPVTLRFTGG WVRDKLLGIG SHDIDIAINK MTGYQFGLRL KQYLEIPGNP EKYGLDGVAT
     TDKENAKAGA SDKSKTVGGL HKIEVNPEKS KHLETVTTRI FALDLDLVNL RKETYTDDSR
     NPQMDFGTPE EDALRRDATV NAMFYNLNTQ EVEDFTGRGH DDLASKIIRT PLEPYQTFKD
     DPLRVLRLIR FASRLGFTID QPALKAMRNA EIKDALQRKI SRERVGVELE KALQGPDPHE
     AMRLIFDLDL YFTLFCDPTT DPAKHYTPDT GGCRALLDEL ETLMEDGSTI SRLLLHAKNE
     QYLAWMLAAA VPYRDAPDPQ PIQPGRKPPP PIPSTVAREG VKATNRVCDV ITASYMHRNE
     IRDLVDRVES HRRRPERANG TSSNPGRDVL GMAVRRWSAS WRSQVLYSLL VAMVEQPDSV
     DAVQRRYSAF LTHLQNLNLL DAYTFKPLLD GKQLAKALNT SPGVWMKDAL DVVMAWQLRN
     PDVKDPTEAI QEVKNHGELT SSLVSHFLQL TVRPLFAKSK PDSLTEQGRK KNDPGLPPKL
     SMMSGNVATT PWKSEKNGVA LDLLAWSVRS LDAKTVEQYW HLLVPPILTL IDDVEIRWKL
     MGVGLLRQTL AATPSSLLER TGLAPVFEDA LMPCLLHLPS LTPEPDSIAL LSTTYPALLA
     LARLQFPITP PSTSKLSPEP SRQLYVKNLD HILRKGILHS HAFCSQYPGI VKVLYDNLTV
     MLWELGIDSI KHIKYILPLL SDTLSHPLVN TAQQQDLLIR ALLALQALIQ NAWPRMVHYR
     GEVLKGLLTC WLAILDAGVE LPVQLGLEMK KTVQMLKDAV AQQVPWDEEM TELTKVDGRL
     VELLQ
//