ID A0A1V9EA00_9BACT Unreviewed; 1202 AA.
AC A0A1V9EA00;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=A4H97_12260 {ECO:0000313|EMBL:OQP42919.1};
OS Niastella yeongjuensis.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niastella.
OX NCBI_TaxID=354355 {ECO:0000313|EMBL:OQP42919.1, ECO:0000313|Proteomes:UP000192610};
RN [1] {ECO:0000313|Proteomes:UP000192610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17621 {ECO:0000313|Proteomes:UP000192610};
RA Chen L., Zhuang W., Wang G.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQP42919.1}.
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DR EMBL; LVXG01000056; OQP42919.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9EA00; -.
DR STRING; 354355.SAMN05660816_03119; -.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000192610; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OQP42919.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000192610};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1202
FT /note="beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010700495"
FT DOMAIN 242..440
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 446..551
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 556..786
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 1202 AA; 136251 MW; 078E437E11732ABB CRC64;
MKKLVVSLLL LSCIHANSQT GFALVEQFNS QPTFYEKTGR GTCKLTNGIL STQEAYASFG
TAQWTNYAIT FKARSQAGKE EVQIWAGFRE YNRNDRYVIG LRGGLQNNLY LSRMGYMGTD
EFLALRPLDF HPVANTWYTF RIEVCDNRIR VFLNNETLPR IDVTDKNSRL APSGKVILGG
GWLPTDYDDL AVKELPDDYF KNIPRKEYSS PQIDKEKKRV TERKAYQAMA INKLSGARTT
VSLNGQWLFM PVYELANEQD AVSPSVGDKN WHSMHVPDFW NPIRIWLHGE TFGPHSKGVS
DVYYRKETER CENYTFDYQK TNAAWYRQWI ELPAGIQDKE TELAFDAVSK VAEVWINGSL
AGKHTGMFGD FKVNGKGLFK PGKNLVAVKV IRDYVKDVKD ANKVIDVAVS VEVTNKMLKD
LAHGFYGNDP AGIWQPVSLV ITDPLKIKDV FIQPSLTGAT FDITIANTSK QDKTFSIATN
IADKKGSLLY KGDALPQTVL HAGEEKKLTY SVKDLKPLLW SPQTPNLYDF TFSVLQSGRI
IDSTVICSGF RTFESKNGYF WLNGKQYWLR GGNQTPFALA PNDRELADRF YEVMKAGNME
VTRTHTAPYN ELWMDAADRK GIGVSFEGTW PWLMLASSMP DRSLIDLWAD EFMDMLKKFR
NHPSLLFWTV NNEMKFYDNE PDLARAKEKM TIISEVVKRM RAVDPTRPMC FDSNYKRKGK
AKRFGDDFMS GIDDGDIDDV HSYINWYDYN IFKMFNGEFQ QENWTAGRPL ISQEMSTGYP
NGETGHPTRF YTLVHQTPQS LIGDLAYEYN NPAYFLEAQS FITGELAEAL RRSNDKAAGF
IHFALLTWFR SVYDAKKIEP YPAYYAMQRA MQPILVSAEL WGRHFYEGAP LPVRICVAND
RTEGTELAAS VLEWKLVGED GKLLQSGTQP VNPVAYYGRE WVTPPITLPA NLPQERVNAK
LLLSLKEKGK EVSANEYKLV LARKEWNAAT GTRKIVLVDR CNLQPVFDFL NLRYTAATDV
NAALQQTADV YVLAGIDSAD LNNEQLQRVR SLVAKGGKLL LLNGPSLAKA LYPEYIRGWF
KPTEGEIVNM DIPESPVFDG LALMDLRYFN NNKREIPTVC NSVLKVNRAA NVELLAKHIR
IHGYINGEMP ERAKHMETIQ GTTIMTIKDN GKAMVSTMSL EKGATDPVAG KLLVNMLNYL
MQ
//
