ID A0A1V9EWK2_9BACT Unreviewed; 814 AA.
AC A0A1V9EWK2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Mechanosensitive ion channel protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A4R26_30020 {ECO:0000313|EMBL:OQP50265.1};
OS Niastella populi.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niastella.
OX NCBI_TaxID=550983 {ECO:0000313|EMBL:OQP50265.1, ECO:0000313|Proteomes:UP000192276};
RN [1] {ECO:0000313|Proteomes:UP000192276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=208 {ECO:0000313|Proteomes:UP000192276};
RA Chen L., Zhuang W., Wang G.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQP50265.1}.
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DR EMBL; LWBP01000220; OQP50265.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9EWK2; -.
DR STRING; 550983.A4R26_30020; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000192276; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192276};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..814
FT /note="Mechanosensitive ion channel protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012280342"
FT TRANSMEM 285..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 644..710
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 719..799
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 814 AA; 91250 MW; 8F87E66680B004DB CRC64;
MKNLFGFLAI VTGLACASPV WAQDTSRAQR NSNITDSSRK QPDTIRRGRG LLRELFADSG
KLTASDFQLQ IEKTYLILNK VGSRSELGLP IKLIKQKLTD TDSMLAVLKD NVLNNSAALN
LRNLQVFKTL LLNIQAESNE DRQVLDSAEN RLIDLRNSMK VLVGDTIMRQ IWRDSLLRQQ
FSPQLKGMRE SFRGATKKLK ESLAKINHFQ TQVSSNIIIT SQLLDRVNAL LSTSAARIFG
KEHNYLWERD TTSLSARARS SMKKAYAGEK KALHYYFKDS NHKRLFLLLI GVVFLVWLLR
NIRTVRRLNA MDSISHFSFE YLPNNYIVAA FIMMFAIAPL FDLHAPSAYI ESMQLLMLVI
LTVICWRKWP RRLFVYWIAM VVLYICFSFT HHMADPGFWQ RNFLILLNIL SVAFGMLFLS
QMQQKLPLRN FLRSVIILHN IMNIVGVLCN ILGRVSLAQI LGSSAIFGFT QAIGLAVFSK
ICMEAILLQI VASRLRRNVH SPMNFEPVLA GFRRPVLFLV VILWLIVFAT NLNIYTSALG
VLGDLLTHQR SIGNATFTIG GVLLFFFIIW IAHLLQKYVG YFFGDTGNDD ETHNKGQRSR
LLIARLILLC VGYLLAVAAS GVPVDKITIV LGALGVGIGL GLQNIVNNFV SGIILIFDRP
LQIGDVVEIG DKSGRVREIG LRSSTLITGD GAEVIIPNGD VLSQQITNWT LSNNQKRIEL
DLSITGSNDM ELVTNTVKKA ILESGFIYEN REPSVLFTGI TDNGVELKVF YWCVDVNKTG
AAKSAITVLL FNALKAQGMQ LGDKANQLIR VING
//
