ID   A0A1V9K4B8_9ACTN        Unreviewed;       249 AA.
AC   A0A1V9K4B8;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:OQQ14423.1};
GN   ORFNames=B0675_30245 {ECO:0000313|EMBL:OQQ14423.1};
OS   Streptomyces sp. M41(2017).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1955065 {ECO:0000313|EMBL:OQQ14423.1, ECO:0000313|Proteomes:UP000192467};
RN   [1] {ECO:0000313|EMBL:OQQ14423.1, ECO:0000313|Proteomes:UP000192467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M41 {ECO:0000313|EMBL:OQQ14423.1,
RC   ECO:0000313|Proteomes:UP000192467};
RX   PubMed=28326787; DOI=10.1021/acs.orglett.7b00545;
RA   Wyche T.P., Ruzzini A.C., Beemelmanns C., Kim K.H., Klassen J.L., Cao S.,
RA   Poulsen M., Bugni T.S., Currie C.R., Clardy J.;
RT   "Linear Peptides Are the Major Products of a Biosynthetic Pathway That
RT   Encodes for Cyclic Depsipeptides.";
RL   Org. Lett. 19:1772-1775(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQQ14423.1}.
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DR   EMBL; MWFK01000002; OQQ14423.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V9K4B8; -.
DR   STRING; 1955065.B0675_30245; -.
DR   Proteomes; UP000192467; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd07721; yflN-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR42951:SF27; BETA LACTAMASE LIKE PROTEIN; 1.
DR   PANTHER; PTHR42951; METALLO-BETA-LACTAMASE DOMAIN-CONTAINING; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:OQQ14423.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192467}.
FT   DOMAIN          20..229
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   249 AA;  26447 MW;  676DD6511BE916A0 CRC64;
     MREEAIVEAA AGVHLVHGSD TNWVVLSEGD AVTLIDTGYP GDRQDLLASL AALGHRPEAV
     TAVLVTHAHT DHLGSAEFLS GSFGTPVLLH EDEVPHARRE FLHQVSIGEV MRQAWRPGVL
     PWAVRALRSG GKADVRMAKP EAFPGTGPLD LPGRPVPVHT PGHTPGHCVY HLPDAGVLIS
     GDALVSGHPT SRARGPQLLH EMFDTERATA LDSLRHIERL EADVLLPGHG PVHHGPVGEA
     AGRARELAG
//