ID A0A1V9K737_9ACTN Unreviewed; 329 AA.
AC A0A1V9K737;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN ORFNames=B0675_35940 {ECO:0000313|EMBL:OQQ15414.1};
OS Streptomyces sp. M41(2017).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1955065 {ECO:0000313|EMBL:OQQ15414.1, ECO:0000313|Proteomes:UP000192467};
RN [1] {ECO:0000313|EMBL:OQQ15414.1, ECO:0000313|Proteomes:UP000192467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M41 {ECO:0000313|EMBL:OQQ15414.1,
RC ECO:0000313|Proteomes:UP000192467};
RX PubMed=28326787; DOI=10.1021/acs.orglett.7b00545;
RA Wyche T.P., Ruzzini A.C., Beemelmanns C., Kim K.H., Klassen J.L., Cao S.,
RA Poulsen M., Bugni T.S., Currie C.R., Clardy J.;
RT "Linear Peptides Are the Major Products of a Biosynthetic Pathway That
RT Encodes for Cyclic Depsipeptides.";
RL Org. Lett. 19:1772-1775(2017).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000256|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000256|HAMAP-
CC Rule:MF_01420}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQQ15414.1}.
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DR EMBL; MWFK01000002; OQQ15414.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9K737; -.
DR STRING; 1955065.B0675_35940; -.
DR OrthoDB; 5197218at2; -.
DR Proteomes; UP000192467; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR NCBIfam; TIGR00647; DNA_bind_WhiA; 1.
DR PANTHER; PTHR37307; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR PANTHER; PTHR37307:SF1; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01420}; Reference proteome {ECO:0000313|Proteomes:UP000192467}.
FT DOMAIN 19..104
FT /note="Sporulation transcription regulator WhiA N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10298"
FT DOMAIN 127..218
FT /note="WhiA LAGLIDADG-like"
FT /evidence="ECO:0000259|Pfam:PF14527"
FT DOMAIN 221..303
FT /note="Sporulation regulator WhiA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02650"
FT REGION 310..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 35093 MW; A79D1CD651CE27D5 CRC64;
MAMTAAVKDE ISRLPVTRTC CRKAEVSAIL RFAGGLHLVS GRIVIEAELD TAMAARRLKR
DILEIFGHSS ELIVMAPGGL RRGSRYVVRV VAGGDQLARQ TGLVDGRGRP IRGLPPQVVS
GATCDAEAAW RGAFLAHGSL TEPGRSSSLE VTCPGPEAAL ALVGAARRLS IAAKAREVRG
VDRVVVRDGD AIGALLTRLG AHESVLAWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAGARVQRAL EILADEVPEH LAAAGRLRME HKQASLEELG ALADPPLTKD AVAGRIRRLL
AMADKRAQDL GIPGTESNLS DEMADNLAV
//
