ID A0A1V9KCC5_9ACTN Unreviewed; 560 AA.
AC A0A1V9KCC5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:OQQ17224.1};
GN ORFNames=B0675_08935 {ECO:0000313|EMBL:OQQ17224.1};
OS Streptomyces sp. M41(2017).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1955065 {ECO:0000313|EMBL:OQQ17224.1, ECO:0000313|Proteomes:UP000192467};
RN [1] {ECO:0000313|EMBL:OQQ17224.1, ECO:0000313|Proteomes:UP000192467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M41 {ECO:0000313|EMBL:OQQ17224.1,
RC ECO:0000313|Proteomes:UP000192467};
RX PubMed=28326787; DOI=10.1021/acs.orglett.7b00545;
RA Wyche T.P., Ruzzini A.C., Beemelmanns C., Kim K.H., Klassen J.L., Cao S.,
RA Poulsen M., Bugni T.S., Currie C.R., Clardy J.;
RT "Linear Peptides Are the Major Products of a Biosynthetic Pathway That
RT Encodes for Cyclic Depsipeptides.";
RL Org. Lett. 19:1772-1775(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQQ17224.1}.
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DR EMBL; MWFK01000001; OQQ17224.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9KCC5; -.
DR STRING; 1955065.B0675_08935; -.
DR Proteomes; UP000192467; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF56; OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DOST; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OQQ17224.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000192467};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 38..187
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 208..351
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 463..560
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 560 AA; 59105 MW; CE41BE30807EFA7A CRC64;
MPGWTAGSGS GPGGPDTELA ARVPRLLEAM RSVGSGLELH STLDRICETA ADLTDARYAA
IGVVSETGHG LTDFVFHGVD HGTAQRIGRL PDGHKGLLGA LVHDPDPVRL TNLAEDPRSC
GFPADHPPMR SFLGVPITVQ GEIFGNLYLA EKRGGGAFGD DDLNMVRVLA TEAGIAIGNA
RLYEAAKQRE RWIDGSVAVT TALLAGGDAE DALQVVAEQA RRLSGSAAGI VLLPAEDGGL
EIVAVASEHP SKALGVVVPP ESQVVAELRE GEPVFVEDAA TDPRMLTDLA RAYGPAMLLP
LQSGGRVVGA LVTPRGRGER PFSESERTLA AQFASQAALA LMMAEAQRDR ERLAVYEDRD
RIARDLHDLV IQRLFATGLM LESAQRRSNV PEVQRGVGKA VDELDITIQE IRTAIFALQQ
GPAEVPSGLR TRVLREINMA AVPLGFKPGH RFVGAVDTVV GELTGKNLIA ALREALSNAF
RHAGASRIDV TVDANVVLPD GRPAVRLSVA DDGVGIPEGG RRSGLRNLKR RAESLGGASW
YGPGLGENGG GTTVVWQVPH
//
