ID A0A1V9KHW2_9ACTN Unreviewed; 853 AA.
AC A0A1V9KHW2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=B0675_19795 {ECO:0000313|EMBL:OQQ19077.1};
OS Streptomyces sp. M41(2017).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1955065 {ECO:0000313|EMBL:OQQ19077.1, ECO:0000313|Proteomes:UP000192467};
RN [1] {ECO:0000313|EMBL:OQQ19077.1, ECO:0000313|Proteomes:UP000192467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M41 {ECO:0000313|EMBL:OQQ19077.1,
RC ECO:0000313|Proteomes:UP000192467};
RX PubMed=28326787; DOI=10.1021/acs.orglett.7b00545;
RA Wyche T.P., Ruzzini A.C., Beemelmanns C., Kim K.H., Klassen J.L., Cao S.,
RA Poulsen M., Bugni T.S., Currie C.R., Clardy J.;
RT "Linear Peptides Are the Major Products of a Biosynthetic Pathway That
RT Encodes for Cyclic Depsipeptides.";
RL Org. Lett. 19:1772-1775(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQQ19077.1}.
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DR EMBL; MWFK01000001; OQQ19077.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9KHW2; -.
DR STRING; 1955065.B0675_19795; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000192467; Unassembled WGS sequence.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR CDD; cd12117; A_NRPS_Srf_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000192467}.
FT DOMAIN 511..586
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 492..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 853 AA; 91261 MW; D52A7098671EE848 CRC64;
MAMIDASVPA AFATQALRSP DAVAVRCAGR ELSYRELDER ANQLAHRLAG LGVGSETPVA
VLMERSVDLV VALLAVLKAG GFYLPLHSGY PLERMQWIVD ETSAPVLLTD RAMRNRGVPG
ASSVVVVDED EELAGLPVGD LGVESRPEQL AYVMYTSGST GRPKGVAVTH RDVLDLVVDG
MFGAGAHERV LMVAPYAFDP STYELWVPLL HGGRTVVTPG DDLSVATLAR LIAEESITGL
QVTAGLFRVM AEEDPGCFAG VREVITGGDV ISPTAVERVL EHCPDTVVRC AYGPTETTLF
ATQAPWDVAD EVPAPIPVGR PLDGMRAYVL DETLAPAPVA VTGELYLAGA GLARGYFGRP
DLTAERFVAD PYGPAGTRMY RTGDLARWSG DGLLEFVGRA DDQVKIRGFR IELGEIEAVL
SRFTGLAQVA VVAREDRSGD KRLVAYVVAE STGTPLDAEA LRTHAAGLLP EYMVPSAFVI
LDQLPLTTNG KLDRRALPEP DAPTKTGTGR GPRTPREEIL CGLFAEVLGV PTVGIYDSFF
ELGGHSLLAT RLASRIRSIL GVKLSIHKLL KTPTVAALST LGQADDEEQD SALEPVLNLR
SVGSRPPLFC VHPGGGMAWC YAGLLRYVPR EHPVYGLQAR GLATDEPYPA DLDEMVEDYL
GRIREIQPSG PYALLGWSFG GKVAHNLAAR LQQEGEQVSL LAVLDAGTAG HASSDSTRSQ
RDLLELAFDG IGAFHAEPGN DPIEMPRILE ILQARGGTLA SLEERTVAAL IDITENNLRI
SRATAPEQFD GDMLFFEAAG PDGASTGLAK VWDPYVSGHI EQHVTPFQHM QLMSSDALAD
LAPVLARALK KQS
//
