ID A0A1V9V0D2_9PSED Unreviewed; 400 AA.
AC A0A1V9V0D2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=4-hydroxytetrahydrobiopterin dehydratase {ECO:0000313|EMBL:OQR35568.1};
GN ORFNames=BWR59_05605 {ECO:0000313|EMBL:OQR35568.1};
OS Pseudomonas sp. Bc-h.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1943632 {ECO:0000313|EMBL:OQR35568.1, ECO:0000313|Proteomes:UP000192462};
RN [1] {ECO:0000313|EMBL:OQR35568.1, ECO:0000313|Proteomes:UP000192462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bc-h {ECO:0000313|EMBL:OQR35568.1,
RC ECO:0000313|Proteomes:UP000192462};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR35568.1}.
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DR EMBL; MUIN01000003; OQR35568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9V0D2; -.
DR STRING; 1943632.BWR59_05605; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000192462; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047920; ZigA-like.
DR NCBIfam; NF038288; chaper_GTP_ZigA; 1.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 255..372
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 400 AA; 45041 MW; 6BD898A4516F75F0 CRC64;
MNRLPVTVLS GFLGAGKSTL LNYVLRNREN LRVAVIVNDM SEINIDGGEV QRDVSLNRAE
EKLVEMSNGC ICCTLREDLL EEVSRLANDG RFDYLLIEST GISEPLPVAE TFTFRDESGQ
SLADIARLDT MLTVVDGLNF LQDYQAAESL DTRGETLGED DERSITDLLI EQVEFADVIL
ISKIDLISSS ERQELMAILK RLNSQAEILP MVMGAVPLGK ILDTGRFDFE RAAHAPGWLK
ELRGEHTPES EEYGIASTAY RARRPFHPQR FFDFINQPWT NGKLLRSKGF FWLASKHQDA
GSWSQAGGLM RHGFAGRWWR FVPRAHWPQD EESTQVIMRN WLAQTGDCRQ ELVFIGQNID
FEQLTADLDG CLLNDAEMAI GVEGWGQLAD PFGDWYGEVA
//
