ID A0A1V9X2J3_9ACAR Unreviewed; 622 AA.
AC A0A1V9X2J3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rab5 GDP/GTP exchange factor-like {ECO:0000313|EMBL:OQR67472.1};
GN ORFNames=BIW11_13504 {ECO:0000313|EMBL:OQR67472.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR67472.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR67472.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR67472.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR67472.1}.
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DR EMBL; MNPL01028734; OQR67472.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9X2J3; -.
DR STRING; 418985.A0A1V9X2J3; -.
DR InParanoid; A0A1V9X2J3; -.
DR OrthoDB; 20678at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.20.5.4770; -; 1.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR045046; Vps9-like.
DR InterPro; IPR037191; VPS9_dom_sf.
DR InterPro; IPR002653; Znf_A20.
DR PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23101:SF122; RAB5 GDP_GTP EXCHANGE FACTOR; 1.
DR Pfam; PF02204; VPS9; 1.
DR Pfam; PF01754; zf-A20; 1.
DR SMART; SM00167; VPS9; 1.
DR SMART; SM00259; ZnF_A20; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR PROSITE; PS51205; VPS9; 1.
DR PROSITE; PS51036; ZF_A20; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000192247};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 12..46
FT /note="A20-type"
FT /evidence="ECO:0000259|PROSITE:PS51036"
FT DOMAIN 239..384
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT REGION 48..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 426..460
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 48..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..613
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 69424 MW; 8FA81083FE6F51BE CRC64;
MSVRRGTLLH VEDRDVYCRN GCQFYGNPEW EGFCSKCYKL IRQQQQQQPQ QQQLHQHSKN
ASSKGKLQLS RQSLSEVRPG GAGDFFGRFE EKKNRQKEQQ RGSKTLKNFI KRANTLKENT
SFSLSSSWTG PVLRDKKASD GLSALREDLY RRLALRQETC LEIIKSLNCA LEKMETFFKK
NEPMSVVSDV IQDVYQLIYD RTVQEAEATT AQEAVELCED FLISHTYDVL FLGLSAEEES
RDLGVLQRIR SLHWVRTHHL ELDIDDIHPT VKEFMDEAMK QLILIDSKRS PKEKLACVVD
AAKNIFKMLQ ASPKGTCYAG ADDFLPAMIF VVLRANPPRL HTNIKLVTLF SAQSRLRSGE
GGYMFTNLCG AVNFIENLTA GELQMPPEEF ELYISGKAVP IEDALTEGAR LMYHNMAALK
ELHLRQDRLA DASEQLKMTL ESLQKDIAEQ VERALEQSEN ARKPHEYRIY RHVPARCLPA
FLRDKVVRID PPASPPQPAD LPAPLQPELL HQGNGAGKNP VDGDSNDITN ENAGGDNNSH
SISSCSANTT STSTDGELVT AGENTIAATP DSAEPSELSA YEVPLAELSQ NSGESPQAED
EAGPEKDSPS ADALSEDQDP SQ
//
