ID A0A1V9X9Y4_9ACAR Unreviewed; 1368 AA.
AC A0A1V9X9Y4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OQR70236.1};
GN ORFNames=BIW11_11759 {ECO:0000313|EMBL:OQR70236.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR70236.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR70236.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR70236.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR70236.1}.
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DR EMBL; MNPL01018181; OQR70236.1; -; Genomic_DNA.
DR STRING; 418985.A0A1V9X9Y4; -.
DR InParanoid; A0A1V9X9Y4; -.
DR OrthoDB; 2910745at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR006573; NHR_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR47508; SAM DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR47508:SF1; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF07177; Neuralized; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00588; NEUZ; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51065; NHR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000192247}.
FT DOMAIN 8..162
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 1017..1086
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 224..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1235..1349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1270..1305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1318..1346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1368 AA; 151105 MW; CBA45107075CB843 CRC64;
MCARLCTTMK FHTTVHGENV TIDEGGKLAC RRSSFCDAVV FLAKPLNVGT RYSLLLAATD
ESWNGALRLG LTTKDPVSLQ PVPKFTFPEL VGQEGFWLAA LPEEFCRAQF RLTFYVSPTG
ELALFVNSGY KGVLLSGLPT SESLFCFIDL FGINTSARLI SHAGGTLVEV LARGPDALRA
YKQSCAAGCV PLRRARLFLV GPQGSGKSTL KRALLGETEP IDGAAQRQQP RQHHHHAQAT
ASPQHIEGND LSRRCLPYHC GNYAYGAMGH YLQVTLLSKL FLASRARAGP GFLEATSANE
RSNTLVFFQS AESMFDSVEC VTAEEGDGAS WLRLREPISS SDASRSSQED DLAKLPENFI
TDEQLEEAIA QNVVKELTLC KRKRQTAQAK QGAVSRTSLR GLRLKRTEPA TAQSSLSFTA
GASSDKEAPG RFTTREEARI TQDLPENIMK LIDGLLKSEA KQEWDSKENE KSSAKTPTFQ
KPVAPMKLTV NIVDLSGDRH LGLSSETFYT PNGIFVLVFD ISKDLDGEDS DMSGLQPPVV
LVGTHVAALH SERDKRLNMV SEKFQRIRDS LKGKLFAVHV VQMYFSLELV DQSAEEDSSI
DELRSKLERI ALRSGALDLD VPLKWLQFER LIGRLVQEQN AFFAGFYQLE EMARQEGLEH
GQEFRSLVHF LHQQGKLFCF GCLHSFQLDS QWDGVIILRP NWFILRCIEL FNISSKNALM
KLSKSYLTEQ VWSKLDDQTG TLISLLDALD ILVESYYEPQ LRRSHHEQNE RCLAVFPWVA
LRSMAPLRFQ NQCSLDTMVF FVDVGSALTE SVYHRFACRL LRWTDWRECD IYKNSLVIPL
DVDHTLLVRV THNNRFIHIM VQRIQRGRED WLASSPPQPS ICEKVRHLVQ AELESLRQSW
YARLSFQLAV ACPCDGAACA LHGLRPCRTC LHLLPLDDCL AKKVVYCDFR RVETEFIRDH
FPYSVIHGMS GGASGANASS GGRRNSLGFA WPQSQLTLNA DALWDEPEWT KEAAKLIGSD
WVALAKRLGY TDRELSRFSE EPAAGLALLR DWRESNGATM YSTDVLISCL QQMEREDIAR
LIQSDEAPQP LVFISYQWHS QEAVLSIRQR LEAAGLPCWM DVGQLGAGNS LYGKIYEGIS
RCKLVLCCLT ARYAASASCA RELSLADVLR RPIVPVMIEP TPWPPPGPMA VILSSLVYVD
LCGVGGHGGY GRDADWNSRC QDIIERANVL IHSTPLAPGP HLPGAPNRRH QITGATSGGP
APVTAQAHAV RGNSPKSHGS ASDSHLQLNM NNARRDSTST VGGTLTPPPA GALSEADERL
SSASSSLGGA SPTLDPSTSG VSDAHGQGEG TMQVVSGRVL RCSVCVLL
//
