ID A0A1V9XGR1_9ACAR Unreviewed; 1931 AA.
AC A0A1V9XGR1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Myosin heavy chain {ECO:0000313|EMBL:OQR72717.1};
GN ORFNames=BIW11_03723 {ECO:0000313|EMBL:OQR72717.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR72717.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR72717.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR72717.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR72717.1}.
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DR EMBL; MNPL01011181; OQR72717.1; -; Genomic_DNA.
DR STRING; 418985.A0A1V9XGR1; -.
DR InParanoid; A0A1V9XGR1; -.
DR OrthoDB; 2877572at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000192247};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 28..76
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 96..759
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 638..660
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 893..922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1219..1921
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 158..165
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1931 AA; 222188 MW; 5D1D25722CC8E612 CRC64;
MASQDPDPTE FLYISAEMKR KDATKPYDGK KMTWVPDEKE GFLLGTIESM EGDKATVDTP
SGKKTFKKDQ LQQVNPPKYE KCEDMSNLTY LNDASTYSGL FCVAINPYKR FPIYTPRVVM
IYKGKRRTEV PPHVFAISDG AYMHMLTDNE DQSMLITGES GAGKTENTKK VISYFANVGK
SEKKADVDSN KPSLEDQIVQ TNPVLEAFGN AKTVRNDNSS RFGKFIRIHF GPSGKLAGAD
IETYLLEKAR VISQQPLERS YHIFYQLMSG KIPDMKKKLL LSNDIHDYYY VSQGKTEIPN
VDDGEEMGLT DEAFDILGFS PEEKDGVYRI TSAVMHFGTM KFKQRPREEQ AEADGTDEGE
NVAKLLGLDT QELYKNLTKP RIKVGTEFVT KGQNQTQVTS AIGALSKAMF DRTFKFLVNK
CNETLDTKQT RKHFIGVLDI AGFEIFDYNG FEQLCINFTN EKLQQFFNHH MFVLEQEEYK
REGIDWVFID FGLDLQACIE LIEKPMGIMS ILEEESMFPK ATDKTFEDKL NSTHLGKSAP
FQKPKPPKSK EIGPAHFAIA HYAGTVSYSI TGWLEKNKDP LNDCVVDQFK KGSLVLLQTI
FEDHPGLGAD AKAEGGGKGG RKKGSGFQTV SGLYREQLNK LMHTLHSTHP HFVRCIIPNE
FKQPRVIDAH LVMHQLTCNG VLEGIRICRK GFPNRMVYPD FRQRYTILAA EEAKKHSEAK
DSSIAVITNI GLEKDEYRFG STKVFFRAGV LGRLEEMRDE RLAKIMTMIQ SACRWYLCKK
HFQKLKEQRL ALRVLQRNLR QFAQMRNWAW WKLFVRVKPL LNMTKAEDEL KALEEKLREE
QEKLAKEEKL RKEFENQNVK LLQEKNELFL QLESERTGAG DIEQRLNKTL AQKNEAERQL
REMEERFHRE EDSANKLNQS KRKLENEISA HKKDIEDLQL SLQKAEQDKQ SKDHQIRNLN
DEIAHQEELV AKLNKEKKAL QEQGGKTSED LQALEDKVNH LNKVKTKLEQ TLDELEDSLE
REKKTRADLD KAKRKVEADL KLAQEAVIDL EKNKKELEHT VQRKDKELTA LAVKLEEEQS
QISKLQKQIK ELQQRVEELQ EELEAERQAR SKAEKQRAGL ARELEQLSER LEEAGGATSA
QIELNKRREA ELGKLRRDLE EANNQHEQVL SALRQKNNVA VAELSDVVDN LNKNKANCYL
MENGFNSKPF FPKRLDKEVS QYKAEADDAR QSVDHLQREK ANAERQVKML EVQLQDTQFK
LDESNRTVND FDAARKKLAL ENADLQRQLE EAESQISQLS KQKASLASQA EEAKRSADEE
NRERAAILGK YRNIEHDLDN LREALEEEQE AKADLQRQLS KANADAQLWR SKYESEGLAR
LEELEESRKR LQIKLQGAEE IIEGLNAKVS GLEKTKSHLQ GELDDMHAEV DRAQQLASQL
EKRQKSFDKV IAEWKAKTDD LAAELDASQK ECRNYSTEVF KLRAAYDESQ EHYEAVKREN
KNLQDELKDL LDQLGEGGRS VHELEKARKR LELEKDELQH ALEEAEVALE QEENKVLRAQ
LELSQVRQEI ERRIQEKEEE FENTRKNHQR ALDSMQASLE AEAKGRAEAL RLKKKLESDI
NELEIALDGA NKANAEAQKT IKRYQQTIKD MQTQIEEEQK ARDEARDQYA NAERRANQLH
GSLEETKQLL EQSERARRSA ENELVELREQ HAEMAANNAS LGMAKRKLEG EMTALQADLD
EMINECKASE EKAKKAMVDA ARLADELRAE QEHASSQEKM RKALEIQMKD LQVRLDEAEA
AALKGGKKLI EKLEHKCRQL ESELETEQRR HADVAKNSRK GERRIKELQF QADEDRKNHE
RMQELVDKLQ QKISTYKRQI EEAEEIAAMN LAKYRKAQQE LEDADERANL AEQTVAKLRA
KNRSTVSMAR E
//
